ID A0A2M9D3B1_9MICO Unreviewed; 392 AA.
AC A0A2M9D3B1;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Adenosylhomocysteinase {ECO:0000313|EMBL:PJJ78535.1};
GN ORFNames=CLV85_2110 {ECO:0000313|EMBL:PJJ78535.1};
OS Salinibacterium amurskyense.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Salinibacterium.
OX NCBI_TaxID=205941 {ECO:0000313|EMBL:PJJ78535.1, ECO:0000313|Proteomes:UP000231742};
RN [1] {ECO:0000313|EMBL:PJJ78535.1, ECO:0000313|Proteomes:UP000231742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16400 {ECO:0000313|EMBL:PJJ78535.1,
RC ECO:0000313|Proteomes:UP000231742};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): From Individual Species to Whole Genera.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
CC -!- SIMILARITY: Belongs to the adenosylhomocysteinase family.
CC {ECO:0000256|ARBA:ARBA00007122}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJJ78535.1}.
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DR EMBL; PGFH01000002; PJJ78535.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M9D3B1; -.
DR OrthoDB; 9802717at2; -.
DR Proteomes; UP000231742; Unassembled WGS sequence.
DR GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1480; Adenosylhomocysteinase-like; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR042172; Adenosylhomocyst_ase-like_sf.
DR InterPro; IPR000043; Adenosylhomocysteinase-like.
DR InterPro; IPR015878; Ado_hCys_hydrolase_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020082; S-Ado-L-homoCys_hydrolase_CS.
DR PANTHER; PTHR23420; ADENOSYLHOMOCYSTEINASE; 1.
DR PANTHER; PTHR23420:SF0; ADENOSYLHOMOCYSTEINASE; 1.
DR Pfam; PF05221; AdoHcyase; 1.
DR Pfam; PF00670; AdoHcyase_NAD; 1.
DR SMART; SM00996; AdoHcyase; 1.
DR SMART; SM00997; AdoHcyase_NAD; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00739; ADOHCYASE_2; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW One-carbon metabolism {ECO:0000256|ARBA:ARBA00022563}.
FT DOMAIN 175..336
FT /note="S-adenosyl-L-homocysteine hydrolase NAD binding"
FT /evidence="ECO:0000259|SMART:SM00997"
SQ SEQUENCE 392 AA; 42049 MW; C51DC41C710C3EEC CRC64;
MTDELIARAA ARLTWIRSRM ALLADVRERF AESQPFAGHR IGMSLHLEPK TAVLLETLAV
GGAEIVATGN HGSTQDDIVA FLRDQGMTIF GARDDTLEQH HANVASVVAA EPDILLDNGA
DLVAGIVAAG RGAQIVGGTE ETTSGGYRLR DELADQVPYP VIVINDSPLK AIGENKHAVG
QSVVESFMRI TNLMVPGRRF VVAGYGWCGR GVAHYLRALG GKVAIVEVDE IKAFEAALDG
YRVANVLDLA DWGEVFITAT GHPQILGAEF FDRVADGAML VNCGHFPWEI DVPALRALAT
GSTEIDTAIE RIDLPGERHV TLIADGRMMN LAGREPKGNS IESMDLGFLL QVLSLEQVAT
ATDTLVAGAQ PVPDSINREI ARRMLATMKA DR
//
