ID A0A2M9E094_9GAMM Unreviewed; 933 AA.
AC A0A2M9E094;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Monovalent cation/H+ antiporter subunit A {ECO:0000313|EMBL:PJJ96335.1};
GN ORFNames=CO641_13875 {ECO:0000313|EMBL:PJJ96335.1};
OS Xanthomonadaceae bacterium NML91-0213.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae.
OX NCBI_TaxID=2032582 {ECO:0000313|EMBL:PJJ96335.1, ECO:0000313|Proteomes:UP000229012};
RN [1] {ECO:0000313|EMBL:PJJ96335.1, ECO:0000313|Proteomes:UP000229012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NML91-0213 {ECO:0000313|EMBL:PJJ96335.1,
RC ECO:0000313|Proteomes:UP000229012};
RA Bernier A.-M., Bernard K.;
RT "Zoonotically transmitted species of Xanthomonadaceae : Genome sequencing
RT and assembly.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJJ96335.1}.
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DR EMBL; NWQL01000006; PJJ96335.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M9E094; -.
DR OrthoDB; 9811798at2; -.
DR Proteomes; UP000229012; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR007182; MnhB.
DR InterPro; IPR025383; MrpA_C/MbhD.
DR InterPro; IPR046806; MrpA_C/MbhE.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR43373:SF1; ANTIPORTER SUBUNIT MNHA2-RELATED; 1.
DR PANTHER; PTHR43373; NA(+)/H(+) ANTIPORTER SUBUNIT; 1.
DR Pfam; PF13244; MbhD; 1.
DR Pfam; PF20501; MbhE; 1.
DR Pfam; PF04039; MnhB; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 460..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 502..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 572..589
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 609..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 635..653
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 659..677
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 697..715
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 756..773
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 794..811
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 817..837
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 857..877
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 897..917
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 65..113
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 129..414
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
FT DOMAIN 617..682
FT /note="MrpA C-terminal/MbhD"
FT /evidence="ECO:0000259|Pfam:PF13244"
FT DOMAIN 692..780
FT /note="MrpA C-terminal/MbhE"
FT /evidence="ECO:0000259|Pfam:PF20501"
FT DOMAIN 794..913
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 933 AA; 99580 MW; ABD0D780231F4D99 CRC64;
MPLTLHLLLS LPFLAAAVVA ALPRTLSRGA VSWTAAAAPL VGLVLLGLMS PAVIDGDILR
ASLPWIPSAG LDLSLRLDGL AWMFAGLVLG IGALIVMYAH YYLDSRDNAP RFYSFLLLFM
GAMLGMVLSG NLLLLVVFWE LTSISSFLLI GFWTHREDAR QGARMALTIT ALGGLALLGG
VLLIGRVVGS FELDAVFAAG DAIRDDTWYP AILGLVLLGI FTKSAQFPFH FWLPQAMAAP
TPVSAYLHSA TMVKAGVFLL ARLHPALAGT DLFFYVVTTV GAITLLVGAW YAIFQHDLKG
LLAYSTISHL GLITMLFGLS TPMAVVAGVF HILNHATFKA SLFMAAGIID HETGTRDMRR
LGNLRRFMPW TAALAIIASL AMAGVPLLNG FLSKEMFFAE ALQVEAQGAM QLFVTVAAGL
AGVLGVAYSL RFVHDTFFGD GPRDLDTDPH EPVRWMRVPV AVLVVMCLAV GVLPALTVSG
ILETAVAGTL GPAAPEFSLA VWHGWNLPLA MSIIGLVGGV FLYFTLRRLF ALHDAMLRSW
GRHLFQVNIE KLFAAAGRFT ERVAAGGIRR SLFWMIVVVL VVGAAPFLGD AAAEAAGYGA
LPSPQPMPLI GWIVWTVLVG STLATVAAHG RRLTALIVIG AVGLMLCAVF ALLSAPDLAL
TQLLVEMVTI ALMMMALNYL PKQSKQARTP FRRWRDAGIS AAAGIGIFAL AYGMLLRPSQ
TISGELLARS LPEAYGANVV NVILVDFRGF DTFGEITVFA VAALVVHALL RWARLKPDEI
MPGPPVQLPI PADLTQLLFP LTLTVSIYLF LRGHNAPGGG FIAGLAIAVP VLIKYVLQGA
RAVEATFGFD YLRGVGLGLL IACIGGLGSL LFGLPFLTSG HYDLELPIVG SLPLTSALVF
DTGVYIVVFA GALLILSTMG TVKHRQRAAE ENY
//
