ID   A0A2M9HER2_9BIFI        Unreviewed;       364 AA.
AC   A0A2M9HER2;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:PJM75295.1};
GN   ORFNames=CSQ87_06375 {ECO:0000313|EMBL:PJM75295.1};
OS   Bifidobacterium simiarum.
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=2045441 {ECO:0000313|EMBL:PJM75295.1, ECO:0000313|Proteomes:UP000231451};
RN   [1] {ECO:0000313|EMBL:PJM75295.1, ECO:0000313|Proteomes:UP000231451}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TRI7 {ECO:0000313|Proteomes:UP000231451};
RA   Mattarelli P., Modesto M., Puglisi E., Morelli L., Spezio C., Bonetti A.,
RA   Sandri C.;
RT   "Draft genome sequences of strains TRE 1, TRE 9, TRE H and TRI 7, isolated
RT   from tamarins, belonging to four potential novel Bifidobacterium species.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PJM75295.1}.
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DR   EMBL; PEBK01000005; PJM75295.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2M9HER2; -.
DR   OrthoDB; 9802008at2; -.
DR   Proteomes; UP000231451; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000231451}.
FT   DOMAIN          11..298
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   364 AA;  39176 MW;  C7CA1B686B5CA045 CRC64;
     MNRDDGLPKA DVIAIAGLGL IGGSLARRLT ARGRRVIAWN HRDAPYAEAR RAGIECVARV
     EDLASAKPDV LVLCTPLRAM PDVLARLAPV LDEATTLTDV GSVKGQVRDE VKAVGLDDRY
     VGAHPMAGNE LSGYAASDPG LYDDALWAVT YDGITDYARL LTVTEMIVRG VGNRVIVLDD
     DTHDRAAALI SHMPHVVATA LANELTETSE RNIAQALAAG SWRDMTRVAL TDPDRTRAMV
     EEDADNVARL LRSVSARLAM MADVLEREGS GDPEDVGRAL AESRGFFAAA RPYREFKARQ
     RARESGTASG AVSANESVDA QALRINVTET GWRDELLESA KRGEHIVGIE SPTTFAVQVR
     TALV
//