ID A0A2M9IDS6_9ACTN Unreviewed; 584 AA.
AC A0A2M9IDS6;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:PJM92805.1};
GN ORFNames=CG719_26190 {ECO:0000313|EMBL:PJM92805.1};
OS Streptomyces sp. CB01373.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2020325 {ECO:0000313|EMBL:PJM92805.1, ECO:0000313|Proteomes:UP000232070};
RN [1] {ECO:0000313|Proteomes:UP000232070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01373 {ECO:0000313|Proteomes:UP000232070};
RA Pan G., Xu Z., Guo Z., Ma M., Yang D., Zhou H., Gansemans Y., Zhu X.,
RA Zhao L.-X., Jiang Y., Cheng J., van Nieuwerburgh F., Suh J.W., Duan Y.,
RA Shen B.;
RT "Discovery of the Leinamycin Family of Natural Products by Mining
RT Actinobacterial Genomes.";
RL Proc. Natl. Acad. Sci. U.S.A. 114:0-0(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJM92805.1}.
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DR EMBL; NNBK01000017; PJM92805.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M9IDS6; -.
DR OrthoDB; 5241249at2; -.
DR Proteomes; UP000232070; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF56; OXYGEN SENSOR HISTIDINE KINASE RESPONSE REGULATOR DOST; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:PJM92805.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000232070};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 55..203
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
FT DOMAIN 224..372
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
FT DOMAIN 484..574
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|SMART:SM00387"
SQ SEQUENCE 584 AA; 62270 MW; B1931031DE5B412D CRC64;
MSGSGESVEA RVRLPQLRLD ELLGELQARL DAARSTRDRV HSLLEAVLAV GRELDLEQVL
YSIVDAAATL VDAEYAALGV IGPDGRRLSA FHTVGVSEEG IARIGPFPEG HGILGELIRH
PEPLRLTKLS EHAASYGFPE HHPPMNTFLG VPIRVRDQVF GNLYLTEKRG GLEFDEDDES
VLATLAVAAG VAIDNARLYE ESRLRERWLR AMAEITQNLM SGADQAEVLG LIAERAREIT
GAALAAMSTP VKETGTLSVE LAIGQEAEAH RGLVLPVEGT LTGEAFTGGV PVSSPDISRD
PRVTAGPPRF AGLGPAVAVP VGGPGDHVRG VVLLVREAGA NDFSSKELEL LKGFAAQAAV
AMELAGRRRD AEQIALLEDR DRIARDLHDL AIQRLFATGM TLQSAGRFID HPGAKERVLR
AVDDLDETIK IVRSTIFGLR AHDEEAGAGL RTRAVQVVGK AAPVLGFAPG VRMEGLLDTH
VSRETADEVV AVLSEALTNI ARHAHADRAE VALETDGRSV RLTVTDNGVG IPAEGRRSGL
SNMAERARRL DGGLEWTTPE GGGTRLVWHV PVGSAEAARS SSKA
//
