ID   A0A2M9IGM5_9ACTN        Unreviewed;       300 AA.
AC   A0A2M9IGM5;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=LysR family transcriptional regulator {ECO:0000313|EMBL:PJM93773.1};
GN   ORFNames=CG719_19810 {ECO:0000313|EMBL:PJM93773.1};
OS   Streptomyces sp. CB01373.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2020325 {ECO:0000313|EMBL:PJM93773.1, ECO:0000313|Proteomes:UP000232070};
RN   [1] {ECO:0000313|Proteomes:UP000232070}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CB01373 {ECO:0000313|Proteomes:UP000232070};
RA   Pan G., Xu Z., Guo Z., Ma M., Yang D., Zhou H., Gansemans Y., Zhu X.,
RA   Zhao L.-X., Jiang Y., Cheng J., van Nieuwerburgh F., Suh J.W., Duan Y.,
RA   Shen B.;
RT   "Discovery of the Leinamycin Family of Natural Products by Mining
RT   Actinobacterial Genomes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 114:0-0(2017).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PJM93773.1}.
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DR   EMBL; NNBK01000012; PJM93773.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2M9IGM5; -.
DR   OrthoDB; 4131546at2; -.
DR   Proteomes; UP000232070; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08423; PBP2_LTTR_like_6; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30346:SF16; SMALL NEUTRAL PROTEASE REGULATORY PROTEIN; 1.
DR   PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000232070}.
FT   DOMAIN          2..59
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   300 AA;  31377 MW;  0ABC0D6C39B04582 CRC64;
     MIEARRLHIL RAVADHRTVT AAAAALYLTP SAVSQQLTAL EQETGHRLVE RGAKGVRLTP
     AGEILLSHTN AVLAQLERAE AELAAYGSGE AGTVTVAAFA TGIAQVVAPA VARLAGTAPG
     IRIRVRDAEG DASLPMVLDR QVDVAVAVEY RGAPSADDPR LTHVPLYAEP FDAVVPVAHR
     LADAAEVQLA ELAKDTWIGP YPGNPCHDVV VLACESAGFQ PRLEHSSDDF RAVVALASAD
     AGVALVPRSA LRGMDLTGVV VRPVDGVAPT RRVFAAVRRG AEGHPLIRPV LQALDEAAQA
//