ID   A0A2M9IKP8_9ACTN        Unreviewed;       419 AA.
AC   A0A2M9IKP8;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=GNAT family N-acetyltransferase {ECO:0000313|EMBL:PJM95159.1};
GN   ORFNames=CG719_14760 {ECO:0000313|EMBL:PJM95159.1};
OS   Streptomyces sp. CB01373.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2020325 {ECO:0000313|EMBL:PJM95159.1, ECO:0000313|Proteomes:UP000232070};
RN   [1] {ECO:0000313|Proteomes:UP000232070}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CB01373 {ECO:0000313|Proteomes:UP000232070};
RA   Pan G., Xu Z., Guo Z., Ma M., Yang D., Zhou H., Gansemans Y., Zhu X.,
RA   Zhao L.-X., Jiang Y., Cheng J., van Nieuwerburgh F., Suh J.W., Duan Y.,
RA   Shen B.;
RT   "Discovery of the Leinamycin Family of Natural Products by Mining
RT   Actinobacterial Genomes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 114:0-0(2017).
CC   -!- SUBUNIT: Homohexamer; trimer of dimers. {ECO:0000256|HAMAP-
CC       Rule:MF_01812}.
CC   -!- SIMILARITY: Belongs to the acetyltransferase Eis family.
CC       {ECO:0000256|ARBA:ARBA00009213, ECO:0000256|HAMAP-Rule:MF_01812}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PJM95159.1}.
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DR   EMBL; NNBK01000008; PJM95159.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2M9IKP8; -.
DR   OrthoDB; 8399956at2; -.
DR   Proteomes; UP000232070; Unassembled WGS sequence.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.630.30; -; 2.
DR   Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR   HAMAP; MF_01812; Eis; 1.
DR   InterPro; IPR041380; Acetyltransf_17.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR025559; Eis_dom.
DR   InterPro; IPR000182; GNAT_dom.
DR   InterPro; IPR022902; NAcTrfase_Eis.
DR   InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR   PANTHER; PTHR37817; N-ACETYLTRANSFERASE EIS; 1.
DR   PANTHER; PTHR37817:SF1; N-ACETYLTRANSFERASE EIS; 1.
DR   Pfam; PF17668; Acetyltransf_17; 1.
DR   Pfam; PF13527; Acetyltransf_9; 1.
DR   Pfam; PF13530; SCP2_2; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   SUPFAM; SSF55718; SCP-like; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315, ECO:0000256|HAMAP-
KW   Rule:MF_01812}; Reference proteome {ECO:0000313|Proteomes:UP000232070};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP-
KW   Rule:MF_01812}.
FT   DOMAIN          8..159
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS51186"
SQ   SEQUENCE   419 AA;  45830 MW;  104E84C67B5CBE6F CRC64;
     MTAASPDIDV RTITEAEIPD WGRALKTGFL RPPGVSEAEI ADLRTYVEPS RTLGAFDAGR
     CVATFRSFPQ EITAVGGATV PADAITNVSV TATHRRRGLL TRMMAQDLAA AKERGDVVAT
     LIAAEYPIYG RYGFGPAAWM TEWAIDVPRA GLDPRRSGPE DGGRVDLVDA EDVRKLGPEL
     HERLRRAQPG AVDRSDRWWQ VSTGVVRPDP SRWTERFHAV YRAADGTVEG LAVYQCDETW
     SDAKQPLNTA TVKDLVAVTP AAERSLWLHL CSIDWIMKVK SGWRASDDLL PHFLPDPRAA
     TVTTHADWLW VRILDVRRAL EARTYEGTGT LILDVLDPAG MAGGRWRLEA SPAGVSCTPT
     TGSADLTLDV AQLATLWLGD ESAVRLAALG RVREERAGAA RGADALLRTS RRPWCPDMF
//