ID   A0A2M9J424_9ACTN        Unreviewed;       949 AA.
AC   A0A2M9J424;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Type 2 lantipeptide synthetase LanM {ECO:0000313|EMBL:PJN01651.1};
GN   ORFNames=CG740_17855 {ECO:0000313|EMBL:PJN01651.1};
OS   Streptomyces sp. CB01201.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2020324 {ECO:0000313|EMBL:PJN01651.1, ECO:0000313|Proteomes:UP000231916};
RN   [1] {ECO:0000313|Proteomes:UP000231916}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CB01201 {ECO:0000313|Proteomes:UP000231916};
RA   Pan G., Xu Z., Guo Z., Ma M., Yang D., Zhou H., Gansemans Y., Zhu X.,
RA   Zhao L.-X., Jiang Y., Cheng J., van Nieuwerburgh F., Suh J.W., Duan Y.,
RA   Shen B.;
RT   "Discovery of the Leinamycin Family of Natural Products by Mining
RT   Actinobacterial Genomes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 114:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PJN01651.1}.
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DR   EMBL; NNBJ01000008; PJN01651.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2M9J424; -.
DR   OrthoDB; 9148343at2; -.
DR   Proteomes; UP000231916; Unassembled WGS sequence.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0031179; P:peptide modification; IEA:InterPro.
DR   CDD; cd04792; LanM-like; 1.
DR   Gene3D; 1.50.10.10; -; 1.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR007822; LANC-like.
DR   InterPro; IPR025410; Lant_dehyd.
DR   InterPro; IPR017146; Lanti_2_LanM.
DR   NCBIfam; TIGR03897; lanti_2_LanM; 1.
DR   Pfam; PF13575; DUF4135; 1.
DR   Pfam; PF05147; LANC_like; 1.
DR   PIRSF; PIRSF037228; Lant_mod_RumM; 1.
DR   PRINTS; PR01950; LANCSUPER.
DR   SMART; SM01260; LANC_like; 1.
DR   SUPFAM; SSF158745; LanC-like; 1.
PE   4: Predicted;
FT   DOMAIN          122..499
FT                   /note="Lantibiotic biosynthesis protein dehydration"
FT                   /evidence="ECO:0000259|Pfam:PF13575"
SQ   SEQUENCE   949 AA;  100769 MW;  A5BA0F326E927742 CRC64;
     MVSAAEPATA DGTQHFARPV RSIARPWRDQ LASRLAELTS LSATERDVLL EAGHTALLRS
     LHAKLSRLFL IELHALRLSG PGADTGSGAV SASGAGAGRA TWDAFIEQAC ADGYLAGLSG
     RYPNLDARIT AVGRLAVAGT ADLAGRLAAD RALLEPLLGA PAGEVRAVEF GAGDSHQGGL
     TVSRVDFAGG TVMYKPRPSE ADVALGALLE DLFQDLPGAP APDRRIRVPG TLARDGYGWA
     EFIRHRYCAD EAELAAFYRN LGHWLAVLRF TGGTDMHAEN MIAAGPVPVI VDAETLFDAP
     APFPPSGRGD AVDAAAAAIR RTVLRTGLLP VRGTGFALGG VDISGIGALP GQQPLIPHPV
     IADGGTAAAR FEVDLVAMPV AGNHPAATPV LSTYWDRVLA GFREMTAHLR RPGLDPHRLL
     ARFEGTRARR ILRPTQAYVD IGRMLWHPAS LHDEPAAIER ARDILRRNAD ALPGAPTDRV
     TIDGEIADLL VGDVPMFGFT VDAPAVRATV ADWRGADLAF EESVIQDALV GAYLNERSLP
     ARVQAAAHDP HARDRERRRR ALAAQMVRRL CDGAVRGEDG TVTWISPVFT PAGWSIRVLP
     ADLYTGQGGV ALTLAEYDRE VRAGRAEQVP GVRETFEGAL RVLIGTEDRT PTPSAGAFSG
     AASQVWTWLA LHRVRGEDWL LRRAAERALL LTAGPLVDED VEVDLLNGAA GAIVPLLDLA
     TVTGRARWLD AAAHIGRRLA KSGVSDAGGV RWPTRLNPEG IGGFAHGATG IGWALTRLAL
     SQAGSAAERA DWSRLGERAF AFQESLYRPV EGNWLDVRIG AEEDFFTSWC HGSAGIGIGM
     LDLHRRTGDP AHLDMARRAA GACAAEGFGW SHTLCHGDLG LWEFLTSIGS GAPEDLDAEI
     LTGLEQRGPV GGLAREAFSP SLMSGLAGVL HTLLRMHPDA DLPNPLLLD
//