ID A0A2M9JET8_9ACTN Unreviewed; 391 AA.
AC A0A2M9JET8;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Acetoin utilization protein AcuC {ECO:0000256|ARBA:ARBA00020218};
GN ORFNames=CG723_45055 {ECO:0000313|EMBL:PJN05398.1};
OS Streptomyces sp. CB01635.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2020326 {ECO:0000313|EMBL:PJN05398.1, ECO:0000313|Proteomes:UP000232157};
RN [1] {ECO:0000313|Proteomes:UP000232157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01635 {ECO:0000313|Proteomes:UP000232157};
RA Pan G., Xu Z., Guo Z., Ma M., Yang D., Zhou H., Gansemans Y., Zhu X.,
RA Zhao L.-X., Jiang Y., Cheng J., van Nieuwerburgh F., Suh J.W., Duan Y.,
RA Shen B.;
RT "Discovery of the Leinamycin Family of Natural Products by Mining
RT Actinobacterial Genomes.";
RL Proc. Natl. Acad. Sci. U.S.A. 114:0-0(2017).
CC -!- PATHWAY: Ketone degradation; acetoin degradation.
CC {ECO:0000256|ARBA:ARBA00005101}.
CC -!- SIMILARITY: Belongs to the histone deacetylase family.
CC {ECO:0000256|ARBA:ARBA00005947}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJN05398.1}.
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DR EMBL; NNBL01000050; PJN05398.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M9JET8; -.
DR OrthoDB; 9808367at2; -.
DR UniPathway; UPA00040; -.
DR Proteomes; UP000232157; Unassembled WGS sequence.
DR GO; GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-UniPathway.
DR CDD; cd09994; HDAC_AcuC_like; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR003085; AcuC.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF13; HISTONE DEACETYLASE HDAC1; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01272; ACUCPROTEIN.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 3: Inferred from homology;
KW Acetoin catabolism {ECO:0000256|ARBA:ARBA00022627};
KW Reference proteome {ECO:0000313|Proteomes:UP000232157}.
FT DOMAIN 22..316
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT REGION 197..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 391 AA; 41673 MW; 929C1E97A35D19F8 CRC64;
MSGRAQLMWD EAVTGYDFGP DHPMDPVRLA LTRSLVGALG LDREVDVVAA KRAGESTLRL
VHREDYVEAV KAASADPASA DGAYGLGTVD DPAFAGMHDV SALIAGQSVG AAEAVWRGEA
LHAVNFAGGL HHAMPGGAAG FCIYNDAALA VARLLELGAE RVAYVDVDVH HGDGVQAAFW
DDPRVLTISL HEHPRTLFPQ TGWPEETGAD GPAEGSAVNV ALPAGTGDAG WLRAFHAVVP
ELLAEFRPQV LVTQHGADTH FEDPLAHLAV SLDAQRAVQV ACHELAHEHA DGRWVALGGG
GYAVVDVVPR SWSHLVGIAA GHEVAPETVI PESWRQEAFA RTRQLAPTRM TDGRWPVSYK
EWEAGYDPAD RLDQAVLATR RSVFPLRGLL P
//
