ID A0A2M9JLK5_9ACTN Unreviewed; 184 AA.
AC A0A2M9JLK5;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=NUDIX hydrolase {ECO:0000313|EMBL:PJN07754.1};
GN ORFNames=CG723_32305 {ECO:0000313|EMBL:PJN07754.1};
OS Streptomyces sp. CB01635.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2020326 {ECO:0000313|EMBL:PJN07754.1, ECO:0000313|Proteomes:UP000232157};
RN [1] {ECO:0000313|Proteomes:UP000232157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01635 {ECO:0000313|Proteomes:UP000232157};
RA Pan G., Xu Z., Guo Z., Ma M., Yang D., Zhou H., Gansemans Y., Zhu X.,
RA Zhao L.-X., Jiang Y., Cheng J., van Nieuwerburgh F., Suh J.W., Duan Y.,
RA Shen B.;
RT "Discovery of the Leinamycin Family of Natural Products by Mining
RT Actinobacterial Genomes.";
RL Proc. Natl. Acad. Sci. U.S.A. 114:0-0(2017).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the Nudix hydrolase family.
CC {ECO:0000256|ARBA:ARBA00005582, ECO:0000256|RuleBase:RU003476}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJN07754.1}.
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DR EMBL; NNBL01000018; PJN07754.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M9JLK5; -.
DR OrthoDB; 177518at2; -.
DR Proteomes; UP000232157; Unassembled WGS sequence.
DR GO; GO:0016462; F:pyrophosphatase activity; IEA:UniProt.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR InterPro; IPR020476; Nudix_hydrolase.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR020084; NUDIX_hydrolase_CS.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR PANTHER; PTHR43046; GDP-MANNOSE MANNOSYL HYDROLASE; 1.
DR PANTHER; PTHR43046:SF14; MUTT_NUDIX FAMILY PROTEIN; 1.
DR Pfam; PF00293; NUDIX; 1.
DR PRINTS; PR00502; NUDIXFAMILY.
DR SUPFAM; SSF55811; Nudix; 1.
DR PROSITE; PS51462; NUDIX; 1.
DR PROSITE; PS00893; NUDIX_BOX; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003476};
KW Reference proteome {ECO:0000313|Proteomes:UP000232157}.
FT DOMAIN 38..171
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 184 AA; 21094 MW; F4466F5D056BDDBC CRC64;
MQWTKQNEQT VYENRWFRVN LADVELPDGR HLDHFVIRLR PVAVATVVNE ANEVLLLWRH
RFITDSWGWE LPAGVVEDGE DIAAAAAREL EEETGWRPGP LRHLMSVEPS NGLEDARHHV
YWAEEGSYVG HPEDDFESDR REWVPLKLVP DMVARGEVPA ANMAAALLML HHLRLGQDAP
GLRR
//
