ID   A0A2M9JT91_9ACTN        Unreviewed;       613 AA.
AC   A0A2M9JT91;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Cholesterol oxidase {ECO:0000313|EMBL:PJN09997.1};
GN   ORFNames=CG723_19940 {ECO:0000313|EMBL:PJN09997.1};
OS   Streptomyces sp. CB01635.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2020326 {ECO:0000313|EMBL:PJN09997.1, ECO:0000313|Proteomes:UP000232157};
RN   [1] {ECO:0000313|Proteomes:UP000232157}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CB01635 {ECO:0000313|Proteomes:UP000232157};
RA   Pan G., Xu Z., Guo Z., Ma M., Yang D., Zhou H., Gansemans Y., Zhu X.,
RA   Zhao L.-X., Jiang Y., Cheng J., van Nieuwerburgh F., Suh J.W., Duan Y.,
RA   Shen B.;
RT   "Discovery of the Leinamycin Family of Natural Products by Mining
RT   Actinobacterial Genomes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 114:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PJN09997.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NNBL01000006; PJN09997.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2M9JT91; -.
DR   OrthoDB; 517968at2; -.
DR   Proteomes; UP000232157; Unassembled WGS sequence.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR000172; GMC_OxRdtase_N.
DR   InterPro; IPR007867; GMC_OxRtase_C.
DR   PANTHER; PTHR47470; CHOLESTEROL OXIDASE; 1.
DR   PANTHER; PTHR47470:SF1; FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF05199; GMC_oxred_C; 1.
DR   Pfam; PF00732; GMC_oxred_N; 1.
DR   Pfam; PF13450; NAD_binding_8; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000232157}.
FT   DOMAIN          217..306
FT                   /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00732"
FT   DOMAIN          498..555
FT                   /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05199"
SQ   SEQUENCE   613 AA;  65046 MW;  C4F4D247723F5418 CRC64;
     MSQENSVRSE AGSDDDAAYD YDVLVVGSGF GGSVSALRLT EKGYRVGVLE AGRRFEPGTL
     PKNSWDLKNY LWAPKFGMYG IQRIHLLGNV MVLAGAGVGG GSLNYANTLY VPPKPFFEDP
     QWKDITDWQA ELKPYYDQAQ RMLGVRLNPT MTPADVHLKA AAQDMGIGDT FHMAPVGVFF
     GDGKDACGED GAGSVKAAPG TQVDDPYFGG AGPARKACTE CGECMTGCRH GAKNTLNENY
     LYLAEKAGAV VHPMTTAVSV TDDSQGGYAV QTLPTDNRKK GAGRTFKARR VIVAAGTYGT
     QTLLHRMKAG GQLPYLSSRL GELTRTNSEA LVGAQTNNRR YKKRHGKSKV DFTQGVAITS
     SIHPDENTHI EPVRYGKGSN AMGGMTILQV PYAQGSSRVA GWLANVAKHP TLMARSLSNH
     RWSERTIIGL VMQSLDNSLT TYLKPDGVGK GLLTAEQGHG APNPKQIKAA VDAASTIAAE
     INGFAGSNIG ELMGTPLTAH FLGGCPIGDS PETGVIDPYH RVYGHPGISV VDGAAVTANL
     GVNPSLTITA QAERAMSYWP NKGEEDPRPA QGVAYARLSA VAPKNPAVPQ DAFGALKLPF
     LGMPAVPPKK TAK
//