ID   A0A2M9JW75_9ACTN        Unreviewed;       528 AA.
AC   A0A2M9JW75;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Long-chain fatty acid--CoA ligase {ECO:0000313|EMBL:PJN11141.1};
GN   ORFNames=CG723_09280 {ECO:0000313|EMBL:PJN11141.1};
OS   Streptomyces sp. CB01635.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2020326 {ECO:0000313|EMBL:PJN11141.1, ECO:0000313|Proteomes:UP000232157};
RN   [1] {ECO:0000313|Proteomes:UP000232157}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CB01635 {ECO:0000313|Proteomes:UP000232157};
RA   Pan G., Xu Z., Guo Z., Ma M., Yang D., Zhou H., Gansemans Y., Zhu X.,
RA   Zhao L.-X., Jiang Y., Cheng J., van Nieuwerburgh F., Suh J.W., Duan Y.,
RA   Shen B.;
RT   "Discovery of the Leinamycin Family of Natural Products by Mining
RT   Actinobacterial Genomes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 114:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PJN11141.1}.
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DR   EMBL; NNBL01000003; PJN11141.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2M9JW75; -.
DR   OrthoDB; 9803968at2; -.
DR   Proteomes; UP000232157; Unassembled WGS sequence.
DR   GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR   CDD; cd17631; FACL_FadD13-like; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:PJN11141.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000232157}.
FT   DOMAIN          22..383
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          433..508
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   528 AA;  57245 MW;  E5948A237DD5127F CRC64;
     MSTDTAPAWS FRHHWMSQAA THAMTRPDKP ALRHLGVTTT WAQLSRRSLQ LAAALADRGV
     AAGDRVALLT LNHPWFVESV FAANSLGAMA VPLNFRLAPP ELDHILTDCT PSAIVVDARL
     LPLLRSVPST ASIGTVVVIG ESSEAEAEDG IAYEDFLSAY EPMELPDISE ESTALIMYTS
     GTTGRPKGVM LSHRNMQVQA ITCIRAMEIF DDSDVGFLTA PFFHIAGLGS MVANFVVGST
     VVIHPLGAFD PQAVLDAYER EGATVVFNVP QQWDLLCAQP DIDKRDLKLR IISWGAAPAS
     DATLRAMGEK FPGALNVAVF GQTETSPITC VLRGEDSLRK LGSVGRPIPS IQYRVVDADM
     NDVAVGEVGE IVYRGPTLTK GYWKKPQETA EAFEGGWFHS GDLVKQDDEG FVWVVDRKKD
     MIISGGENIY CAELENAVAT HPNVREVAVI SRADERWGQV PVAYVAVTPG ADLSLRELTG
     FLEGKLASFK RPKDLVLVTE LPRNAGGKVV KSLLRTQDAA RVPGQDEE
//