ID A0A2N0VGW4_9BACT Unreviewed; 630 AA.
AC A0A2N0VGW4;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN Name=acs {ECO:0000313|EMBL:PKD43413.1};
GN ORFNames=CWD77_10560 {ECO:0000313|EMBL:PKD43413.1};
OS Rhodohalobacter barkolensis.
OC Bacteria; Balneolota; Balneolia; Balneolales; Balneolaceae;
OC Rhodohalobacter.
OX NCBI_TaxID=2053187 {ECO:0000313|EMBL:PKD43413.1, ECO:0000313|Proteomes:UP000233398};
RN [1] {ECO:0000313|EMBL:PKD43413.1, ECO:0000313|Proteomes:UP000233398}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=15182 {ECO:0000313|EMBL:PKD43413.1,
RC ECO:0000313|Proteomes:UP000233398};
RA Han S.;
RT "Rhodohalobacter 15182 sp. nov., isolated from a salt lake.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKD43413.1}.
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DR EMBL; PISP01000003; PKD43413.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N0VGW4; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000233398; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:PKD43413.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000233398}.
FT DOMAIN 9..63
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 69..459
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 514..592
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 630 AA; 71176 MW; 933E7F03A9C0F65C CRC64;
MNIKSFEEYK EVYEQSEKDR EKFWEHEAGT FYWRKSWDKV HSGGFENGDI KWFEGGKLNI
TENMLDRHLN TIGHKTAFIF EPNHPDSFRR TITYRQLHED VCRFANVLES KGIEKGDRVC
IYMAMTPELI ISALACARIG AVHSIVFAGF SAQSLAERIQ DCDAKMLITN DGLRRGDKHV
PLKEISDEAL ENCPTVKNVI VCQRTNREIG WVEGRDEWWH MLIRNASKRH KAVEMDAEDP
LFILYTSGST GKPKGVLHTC GGYMVYTSYT FRNVFQVEEE DVYWCTADAG WITGHSYIIY
GPLFNGATGI IFEGTPTYPD PGRFWEVVEK YRVTHFYTAP TAIRALMSYD INYVQKYDLS
SLKVLGSVGE PINEEAWHWY NDHVGGGRCP IVDTWWQTET GGISISPLAG ITPTKPGFAT
LPLPGISPVL MDENGKEIEG NGVNGNLCIK HPWPGIARTI WGDHERYLKT YMSTYKGYYF
TGDGCRRDAD GYYRITGRVD DVLNVSGHRL GTAEIENAID EHPNIVEAAI VGYPHDVKGQ
GIFAFMVCEK DPKDPEAFKG EIHDLVTKII GPIAKPDKVQ IVSGLPKTRS GKIMRRILRK
IAAKDLENIG DTSTLLDPAV VEDIKKGKAY
//
