ID A0A2N0WQ65_9GAMM Unreviewed; 1141 AA.
AC A0A2N0WQ65;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=GGDEF domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CW748_08730 {ECO:0000313|EMBL:PKF56560.1};
OS Alteromonadales bacterium alter-6D02.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales.
OX NCBI_TaxID=2058087 {ECO:0000313|EMBL:PKF56560.1, ECO:0000313|Proteomes:UP000233605};
RN [1] {ECO:0000313|EMBL:PKF56560.1, ECO:0000313|Proteomes:UP000233605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=alter-6D02 {ECO:0000313|Proteomes:UP000233605};
RX PubMed=27311813; DOI=.1038/ncomms11965;
RA Datta M.S., Sliwerska E., Gore J., Polz M.F., Cordero O.X.;
RT "Microbial interactions lead to rapid micro-scale successions on model
RT marine particles.";
RL Nat. Commun. 7:11965-11965(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKF56560.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PIZK01000014; PKF56560.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N0WQ65; -.
DR OrthoDB; 9816034at2; -.
DR Proteomes; UP000233605; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 4.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR011620; Sig_transdc_His_kinase_LytS_TM.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 4.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF07694; 5TM-5TMR_LYT; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08448; PAS_4; 2.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 4.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 3.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233605};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 206..276
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 279..331
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 332..402
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 404..453
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 454..526
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 654..706
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 738..871
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 880..1134
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1141 AA; 127961 MW; B7C18CA3BD68CECA CRC64;
MDSFAALLNN VVLLLALTVI YDAFSLANIK QQQWRDLATG LFVGVIAISV MLTPWELRPG
VFFDSRWVLI SLCALYFGLV PTLIAITMAV AMRFYQGGGG AYVGSWVILS SGLLGLIAKQ
WCLPSIKHIN WKSLYLFSVV IELNVLLCMF LMPEAVRYQI IASIAPTLLV IFPLASTLIG
MLLKRQQERR NDAAELAENK RLLAREKGIL KSLIDSIPDL IFYKTSESEY IGCNKAFEGF
IGHSEDFLIK KTDHDLFDPE LADFFREKDR LMLAAGGTQS NEEWVEYPDS RKVLLDTVKT
PLRTENGEVF GLVGISRDIT SKHQDAERIK ESELVHRSII HTAIDGFWVL SIDGDITDTN
AAYCQMSGYS SDELLTMSIN ELDASYNEQE LSGIIDYIMA GAEQRFTTQH RRKDGSTYFV
EVNATYWPNN GGKFFVFIRD ITERQQSQQV LKESETRFRH LCESMPKIAV QGYDKEHEVI
FWNDASETLY GYSSQQAIGN TLESLIVPES YVKTETLRMK QWFDQGSAGA AEEVVRQNAQ
QQHINVFSTR VLIRNLNNEV ELYCIDIDLT AQKLAEERAI VLTQALEQSP ISVMITDKEG
FIEYVNQAFI AESDGAEGNE LVAIGGRSSL LSAHEGFEDG YEGIWKTVAQ GKQWQGELEI
KQANSESLWQ LVNVTPIFSS NGNINHYLTV KQDITQQKEQ ELKIVQQAHF DNLTGLPNRF
LALDRLRHML AEAKRLNHKL AVLFLDFDDF KKVNDTLGHS AGDELLVEAS CRLQNAVRES
DVVGRLGGDE FIILVHVEGE PSQLSIIADK LLEQFRTPFV ISGREFVSTI SIGIAIFPDD
SQNPQELLRQ ADSAMYHSKE LGRNTYNFYT EQMNLDIARR VLIEEQLRLA LAQNELFLCY
QPLVDLNTLD VIGAEALLRW NNSVLGNVTP DEFIPIAEQT GLIVDIGSFV LRTASAALAR
WRSQGFEHLR VSINVSPLQF REGLLLKEVQ TLLTQVNLPS SAIELEITEG VLISGYGDVS
STLHGLNDLG ISIAMDDFGT GYSSLSYLRK YPFDTLKIDK DFVDDICLDE ADAKLVAAAV
SMGHALKLKV LAEGVETAEQ LEALVKLGCD LGQGYLFGKP MLIEDFERQV FEPRLGDVTS
K
//
