ID A0A2N0ZYM8_9GAMM Unreviewed; 814 AA.
AC A0A2N0ZYM8;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=CXF74_18095 {ECO:0000313|EMBL:PKG37597.1};
OS Psychromonas sp. Urea-02u-13.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Psychromonadaceae; Psychromonas.
OX NCBI_TaxID=2058326 {ECO:0000313|EMBL:PKG37597.1, ECO:0000313|Proteomes:UP000233836};
RN [1] {ECO:0000313|EMBL:PKG37597.1, ECO:0000313|Proteomes:UP000233836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Urea-02u-13 {ECO:0000313|EMBL:PKG37597.1,
RC ECO:0000313|Proteomes:UP000233836};
RA Collins E., Ducluzeau A.-L.;
RT "Pharmacopeia of the Arctic Ocean.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- SIMILARITY: Belongs to the DnaX/STICHEL family.
CC {ECO:0000256|ARBA:ARBA00006360}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKG37597.1}.
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DR EMBL; PJBZ01000097; PKG37597.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N0ZYM8; -.
DR OrthoDB; 9810148at2; -.
DR Proteomes; UP000233836; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd18137; HLD_clamp_pol_III_gamma_tau; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.30.300.150; DNA polymerase III, tau subunit, domain V; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR022754; DNA_pol_III_gamma-3.
DR InterPro; IPR012763; DNA_pol_III_sug/sutau_N.
DR InterPro; IPR021029; DNA_pol_III_tau_dom-5.
DR InterPro; IPR045085; HLD_clamp_pol_III_gamma_tau.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038249; PolIII_tau_V_sf.
DR NCBIfam; TIGR02397; dnaX_nterm; 1.
DR PANTHER; PTHR11669:SF0; PROTEIN STICHEL; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR Pfam; PF12169; DNA_pol3_gamma3; 1.
DR Pfam; PF12170; DNA_pol3_tau_5; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022932};
KW Transferase {ECO:0000256|ARBA:ARBA00022932}.
FT DOMAIN 37..179
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 814 AA; 89909 MW; 090EDD9DF19ECF3E CRC64;
MSYQVLARKW RPHNFSQVVG QQHVLTALSN GLTQNRVHHA YLFSGTRGVG KTTIARILAK
SLNCEQGVTA TPCGKCENCV AIDQGRFVDL LEIDAASRTK VDDTRELLDN VQYKPAVGRY
KVYLIDEVHM LSKHSFNALL KTLEEPPEYV KFLLATTDPQ KLPITVLSRC LQFHLKAILP
DQIEAQLAHI LKHEDATFEY TALNVIAKAA DGSMRDALSL TDQALAFGAG NIEYQSVLKM
LGTLDNSHLH YLLHFIASGN VAKVFQKIEE FVVLGADFAK LHQELAGLCH QIALQQLQRP
QANSEKSAIQ LLSERLSPEE VQLYYQIALE GYKDYRFAPN GKVALEMTVM RLLAFKPANY
IELDEKALVN NTLVNTTVQS EGNIDLPSFN PAPESIQPAA LIETTPVVEQ VSVIGNDSSP
SLPETRLPEP APVTVVETLT AQEMPVPTPV IETSPVQDVS SQPMPNQQAP SQQAVIETPP
VQEAPANSPA VEVAAPITEA VPVPVKSEPV LESSNSRNML RSHRLKRNET KKSQATTDHV
ISTPVVAALP KVDNIIPDVA AKKTDLPITP VIQTDNVTSA PNRQNFSPEL PPIEQYQESE
QADNRFDSQF DSPYDQFENN SYDPYSPPEE MQSVNTQVAA LPSVSNNVQA PVIDNSALNT
GIVTKHASFS DQHFEAVEID KAKYVEDKLT DSWSLAIQTM QVRGLVKLLA KNSVMKKVDD
QIVLTLKAEH QHLLNNSGLC EELQMQLKSF YGAQYNMYIE VGNVEGQLTA FESEMALYEQ
YLNNAKHAIV DDENIKALVA NCGAKVYENS VIPL
//
