ID   A0A2N1D243_9ALTE        Unreviewed;      1163 AA.
AC   A0A2N1D243;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=LTD domain-containing protein {ECO:0000259|PROSITE:PS51841};
GN   ORFNames=CXF95_25480 {ECO:0000313|EMBL:PKG95650.1};
OS   Paraglaciecola sp. MB-3u-78.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Paraglaciecola.
OX   NCBI_TaxID=2058332 {ECO:0000313|EMBL:PKG95650.1, ECO:0000313|Proteomes:UP000233828};
RN   [1] {ECO:0000313|EMBL:PKG95650.1, ECO:0000313|Proteomes:UP000233828}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MB-3u-78 {ECO:0000313|EMBL:PKG95650.1,
RC   ECO:0000313|Proteomes:UP000233828};
RA   Collins E., Ducluzeau A.-L.;
RT   "Pharmacopeia of the Arctic Ocean.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the EndA/NucM nuclease family.
CC       {ECO:0000256|ARBA:ARBA00006429}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKG95650.1}.
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DR   EMBL; PJCF01000015; PKG95650.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N1D243; -.
DR   OrthoDB; 9800417at2; -.
DR   Proteomes; UP000233828; Unassembled WGS sequence.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR007346; Endonuclease-I.
DR   InterPro; IPR020008; GlyGly_CTERM.
DR   InterPro; IPR044925; His-Me_finger_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR001322; Lamin_tail_dom.
DR   NCBIfam; TIGR03501; GlyGly_CTERM; 1.
DR   PANTHER; PTHR33607; ENDONUCLEASE-1; 1.
DR   PANTHER; PTHR33607:SF2; ENDONUCLEASE-1; 1.
DR   Pfam; PF04231; Endonuclease_1; 1.
DR   Pfam; PF00932; LTD; 4.
DR   SUPFAM; SSF54060; His-Me finger endonucleases; 1.
DR   PROSITE; PS51841; LTD; 3.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022722};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233828};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..1163
FT                   /note="LTD domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014845465"
FT   DOMAIN          12..134
FT                   /note="LTD"
FT                   /evidence="ECO:0000259|PROSITE:PS51841"
FT   DOMAIN          201..321
FT                   /note="LTD"
FT                   /evidence="ECO:0000259|PROSITE:PS51841"
FT   DOMAIN          394..509
FT                   /note="LTD"
FT                   /evidence="ECO:0000259|PROSITE:PS51841"
SQ   SEQUENCE   1163 AA;  122801 MW;  1A66E0C4FF094C37 CRC64;
     MKQIFKKAML TTALSCLLSA TAMANVVITE YVEGSSSNKA IEISNLGSAA VDLAADEYKL
     ALYSNGSVDE GNTELLTGTL SPNASLVIYN SGADPEFIFD APNGIASTVT FFNGDDAILL
     TKADVVVDSF GRVGEDPGSA WTDANDADFS TANKTLRRLS SVTTGDAISD DAFPGTSIEW
     LTFDSNTADG LGCSGETLCS NDNTGGDPAA ASILITEYIE GGGSNKAIEI TNISSTDVDL
     GAGAYKLALY SNGSVDEGNT ELLTGTLAPN ASLVIYNSGA DPEFIFDAPN GVASTVTFFN
     GDDAIVLTKA DVVVDSFGRV GEDPGSAWTD ANDADFSTAN KTLRRLSSVT TGDTVVDDAF
     PGASNEWLTF DRDTADGLGC AGEVACSDDN TGGGDPVAQI VLITEYIEGG SSNKAVEITN
     LGSTDVDLGA GEYKLALYSN GSVDEGNTEL LIGTLAPNAS LVIYNASADP EFVFDAPNGI
     SSQVTFFNGD DALVLTKAGI VVDSFGRVGE DPGSAWTDAN DADFSTANKT LRRLSSVTTG
     DTVIDDGFPG GASNEWLTFD QDTSDGLGCP GEGVCTNDNT GGGNPVNANV LITEYIEGGS
     NNKAFEISNL GTESVDLFTA GYRLEAFNNG NTDASNSENL IGILVPNSSI VIFNSGADEV
     FKKLAPQGIA SNVTFINGDD ALVLTVNGTI VDSLGRIGED PGSEWTDPND ANFSTANKTL
     RRLSTVTTGD IIVDDVFPNT PNEWVVFDKD TSDGLGCPGE TACTGNEPLP LEGEGIVPQT
     GLCLNCPDIT KIADATTFIA SDYYAVALAA DPADLRNEVN TIISTNHTQL SYGEVWSVLT
     FSDEDPDNSD NIITLYRGDS LPKFSNGSGA QSSDPDAWNR EHVWSKSHGF PNQSQLGYTD
     AHHLRPADAS VNSTRSNYDF EAGGIPVAES PLNSVDSANR TFEPRDEVKG DVARMMFYMD
     VRYAGASTED TPDLILVDNI GTDTGSPEFG KLCTLYDWHL IDVVSAAETQ RNDVVYEYQG
     NRNPFIDYPE WVDTIFGSIC MPNTPPEINI TGDAVVSEGA MVTIDASGSS DFDNDQLTYQ
     WVQLTSELIS FDTSAATLSF RAPQVSDDIP IRFQLTVSDG LSTVTTTYNV VVENNESGGS
     MAWLSLLLLS MLHIRNRKTK FNS
//