ID   A0A2N1DF67_9ALTE        Unreviewed;       498 AA.
AC   A0A2N1DF67;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000313|EMBL:PKH00222.1};
GN   Name=mmsA {ECO:0000313|EMBL:PKH00222.1};
GN   ORFNames=CXF95_06350 {ECO:0000313|EMBL:PKH00222.1};
OS   Paraglaciecola sp. MB-3u-78.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Paraglaciecola.
OX   NCBI_TaxID=2058332 {ECO:0000313|EMBL:PKH00222.1, ECO:0000313|Proteomes:UP000233828};
RN   [1] {ECO:0000313|EMBL:PKH00222.1, ECO:0000313|Proteomes:UP000233828}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MB-3u-78 {ECO:0000313|EMBL:PKH00222.1,
RC   ECO:0000313|Proteomes:UP000233828};
RA   Collins E., Ducluzeau A.-L.;
RT   "Pharmacopeia of the Arctic Ocean.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKH00222.1}.
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DR   EMBL; PJCF01000003; PKH00222.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N1DF67; -.
DR   OrthoDB; 9812625at2; -.
DR   Proteomes; UP000233828; Unassembled WGS sequence.
DR   GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:InterPro.
DR   CDD; cd07085; ALDH_F6_MMSDH; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR010061; MeMal-semiAld_DH.
DR   NCBIfam; TIGR01722; MMSDH; 1.
DR   PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR43866:SF3; METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233828}.
FT   DOMAIN          15..478
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
SQ   SEQUENCE   498 AA;  53929 MW;  AB4FADDADBA66B6F CRC64;
     MHLVPSLING ELVTSTSLPN IAVTNPANNK VIAELTCTTD AELALAVASA KAAFEDWKEV
     PASERARVMM RYQHLLKEHH EEIATILSSE TGKTLADAKG DVWRGIEVVE QAMNIPSMMM
     GETAENVARG IDTYSYIQPL GVCLGITPFN FPAMIPLWMF PMAIACGNTF ILKPSEQDPL
     TPMKLAELFV QAGAPKGVLN VVHGGKDQVN ALLKDPDIRA VSFVGSVPVG QHIYKTATDN
     MKRAQCFAGA KNHSVIMPDS NKQQVINNLV GASVGAAGQR CMAISVAVFV GESKEWIGEL
     TELLKAVKPG LWDDESAGFG PLISPQAKQK VLSLIQQGKD EGATCLLDGS GFVLDKEGYQ
     QGNWVGPTVF ADVSEDMVIY QEEIFGPVLC CMTVDTLEEA IALVNRNPYG NGTSIFTASG
     AAARKYQHEI EVGQVGINVP IPVPLPFFSF TGWKNSFYGD LHAYGKQAVR FYTETKTITA
     RWFEDDIPSG PNMTISLK
//