ID   A0A2N1J6U2_9BASI        Unreviewed;       554 AA.
AC   A0A2N1J6U2;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=DNA polymerase epsilon subunit {ECO:0000256|PIRNR:PIRNR000799};
DE   AltName: Full=DNA polymerase II subunit 2 {ECO:0000256|PIRNR:PIRNR000799};
GN   Name=DPB2 {ECO:0000313|EMBL:PKI82271.1};
GN   ORFNames=MVES_003813 {ECO:0000313|EMBL:PKI82271.1};
OS   Malassezia vespertilionis.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX   NCBI_TaxID=2020962 {ECO:0000313|EMBL:PKI82271.1, ECO:0000313|Proteomes:UP000232875};
RN   [1] {ECO:0000313|EMBL:PKI82271.1, ECO:0000313|Proteomes:UP000232875}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NWHC:44797-103 {ECO:0000313|EMBL:PKI82271.1,
RC   ECO:0000313|Proteomes:UP000232875};
RA   Lorch J.M., Palmer J.M., Vanderwolf K.J., Schmidt K.Z., Verant M.L.,
RA   Weller T.J., Blehert D.S.;
RT   "A novel species of cold-tolerant Malassezia isolated from bats.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Participates in DNA repair and in chromosomal DNA
CC       replication. {ECO:0000256|PIRNR:PIRNR000799}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PIRNR:PIRNR000799}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase epsilon subunit B family.
CC       {ECO:0000256|ARBA:ARBA00009560, ECO:0000256|PIRNR:PIRNR000799}.
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DR   EMBL; KZ454998; PKI82271.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N1J6U2; -.
DR   STRING; 2020962.A0A2N1J6U2; -.
DR   OrthoDB; 166885at2759; -.
DR   Proteomes; UP000232875; Unassembled WGS sequence.
DR   GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR   Gene3D; 3.60.21.60; -; 1.
DR   InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR   InterPro; IPR016266; POLE2.
DR   PANTHER; PTHR12708:SF0; DNA POLYMERASE EPSILON SUBUNIT 2; 1.
DR   PANTHER; PTHR12708; DNA POLYMERASE EPSILON SUBUNIT B; 1.
DR   Pfam; PF04042; DNA_pol_E_B; 1.
DR   PIRSF; PIRSF000799; DNA_pol_eps_2; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW   ECO:0000256|PIRNR:PIRNR000799};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR000799};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR000799};
KW   Reference proteome {ECO:0000313|Proteomes:UP000232875}.
FT   DOMAIN          309..521
FT                   /note="DNA polymerase alpha/delta/epsilon subunit B"
FT                   /evidence="ECO:0000259|Pfam:PF04042"
SQ   SEQUENCE   554 AA;  61574 MW;  F3608171438EDBE8 CRC64;
     MADVHVPPDV RREILRAFTR KYHLQLRSDA VQFVCATLQA HGLLDEPVAR AEAVEALANA
     LVEQHFSGAS SAGFDGLVVT SDVLCKVYDQ LVVEGAEEPG AASAVTMGDT PNLERYFHVC
     DAFKLPRIRF NGSRKIFEPI EKPASLLSSP ASVTEHLAER YELLRSVVLR NEHFLPPLAA
     GARESHMKLT TTKNLLGRQG QNCLLFGRLS TTPDGQYVLE DTEGSVHLDL DAAIAGEGIF
     TEGSFVLVEG EYTMQERLHA FAIGHPPSES RDEARSLFGH VDFTGTGAVP QKHVAAMQSQ
     EMQHPDLSFA VFSDVHLDHE NSLSNLRAIL QGYGDADFIP FCLVLCGNFT SVSMEADEGN
     RDRFEQGFLR LAELLQRFPH ILEQTHLVLI PGPADPVSTP LLPRARIPAP LVASFEQSLP
     SAFVAQRLHW ASNPCKLVYF SQEMVIFRDD IMSKMLRSAV RLKDELRDGD LQKFLVSTLL
     DQAHLCPLPQ QVRPVLWEHA NAMRLYPMPS ALVLADRYER FELTYEGCHV FNPGSFRDGA
     EVRALLVNTS ELQE
//