ID A0A2N3HNR4_9FLAO Unreviewed; 1337 AA.
AC A0A2N3HNR4;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CSW08_02370 {ECO:0000313|EMBL:PKQ46623.1};
OS Confluentibacter flavum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Confluentibacter.
OX NCBI_TaxID=1909700 {ECO:0000313|EMBL:PKQ46623.1, ECO:0000313|Proteomes:UP000233435};
RN [1] {ECO:0000313|EMBL:PKQ46623.1, ECO:0000313|Proteomes:UP000233435}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3B {ECO:0000313|EMBL:PKQ46623.1,
RC ECO:0000313|Proteomes:UP000233435};
RA Yu L.;
RT "Confluentibacter flavum sp. nov., isolated from the saline lake.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKQ46623.1}.
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DR EMBL; PJEO01000011; PKQ46623.1; -; Genomic_DNA.
DR OrthoDB; 1522078at2; -.
DR Proteomes; UP000233435; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 4.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 2.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Kinase {ECO:0000313|EMBL:PKQ46623.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000233435};
KW Transferase {ECO:0000313|EMBL:PKQ46623.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 784..807
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 842..1056
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1088..1203
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1235..1334
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT MOD_RES 1136
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1337 AA; 153172 MW; CB4554A694E07A85 CRC64;
MKTNKTLLYF TIVFWIITLQ NTIGQSSYIF RHLNTNDGLS NASVKAILRD SYGFLWVGTE
SGLNRYDGYG FKVYNANSKM PHSLESNDVM GLQEDGLGNI WVDLGFTYMV YNREKDHFIS
EKESFFKELN IQAVDNSKIY VDKKQNLWVL NREKVFCYNI KKKTTSGFNL EIPLDDIGNV
NITDNGDSLF VISQSGEFWQ LNVNSGKQTI IKLPNFIMQA INKYFNKIYV DSNNGLWLHS
NMADVVFYRK HPNSEWMTIE LKSEIQTDGN SITSIIENRP GQIWIVTDHK GVFVYNKAKG
SIENIISDPW ESSTLSSNSI KCIYRDSNET VWIGHSKKGL SYYHESFRNI MNFEHPECSD
ISVIMEDHLE NIWLGTDGNG LFVKDKKLGN GVIKLPIPNV AIVSILEDRA NRIWIGTFQK
GLYCYENGKM VQYTTGNSKL SNNNIWDIEE DRYGNIWIGT LGGKIQLLPS ESSNFDFLLS
PFEEDTAVLD MFYDGGDKVY AGTVSGLLEI DITTKKHVIY FSNINGTQRF LRDAVTNVYK
DNRDILWLGH NIGLTIWDKK TDKIYYFNKA KGLCDDSIKG IVSDNLNNIW VTTSNGLSIL
TADRDLDNNL SITSKNYSVK DGLMDNFFNA HSISKLKNGD ILLGNIDGYS IFNPNKMEEK
NRPLAKVKFT GLTVSNQKIQ VDSIYNGHKL LERPMELTSD LIFKYNDKLI SLQFTTGDLL
NADKIRYAYQ IEGFNTEWIP TQENKIELST LHPGEYKLLI KASNSDGVWN NDPTILNIKV
TPPFYFSIWA IVLYALATIG IIIYFILRSK RRHLIKLEQH RIRMDREKEM QVNEMKLKFF
TNISHDLRTP LTLIITPLQV LLNETMEENM KKKLSTIYKN AQQLLSLINS LLDFRKLDVG
IDTLNLKPGD FVDFVRDIYL SFSVYANERH INLSLSNEID NLLMQFDRDK IQKTLTNLLS
NAFKYTSDGG AINIHIDSYD DYVYVSVSDS GPGISDEDKE HVFERFYQAQ QKQDKTGSGI
GLHIANEYVN LHGGAITLTD NIPYGCVFTI KLPIREISQT ENLYSYNTSD EDVLEDVVKL
DAINNKPLLL FVDDNKDFCG FMVDNLEDEY SVITANNGLE AIEQLNKQDV TIVISDVMMP
IMSGTELCEK IKTNIYWSHI PVILLTARAA EEHQIEGLEL GADDYITKPF NFNLLRLRIR
KFIEWTERSH NIFSQKLDVA PSEITITSLD EKLIEKAIKV VEDHISNSEF SVETLGMAVG
LSRGHLYKKL MVITGKGPSE FIRTIRLKRG RQLLEKSQLQ ISEIAYEVGF NSPKRFTKYF
RDEFGVLPSE YLRIHKE
//
