ID   A0A2N3N1B2_9PEZI        Unreviewed;       345 AA.
AC   A0A2N3N1B2;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN   ORFNames=jhhlp_006961 {ECO:0000313|EMBL:PKS06215.1};
OS   Lomentospora prolificans.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Microascales; Microascaceae; Lomentospora.
OX   NCBI_TaxID=41688 {ECO:0000313|EMBL:PKS06215.1, ECO:0000313|Proteomes:UP000233524};
RN   [1] {ECO:0000313|EMBL:PKS06215.1, ECO:0000313|Proteomes:UP000233524}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHH-5317 {ECO:0000313|EMBL:PKS06215.1,
RC   ECO:0000313|Proteomes:UP000233524};
RX   PubMed=28963165; DOI=10.1534/g3.117.300107;
RA   Luo R., Zimin A., Workman R., Fan Y., Pertea G., Grossman N., Wear M.P.,
RA   Jia B., Miller H., Casadevall A., Timp W., Zhang S.X., Salzberg S.L.;
RT   "First Draft Genome Sequence of the Pathogenic Fungus Lomentospora
RT   prolificans (Formerly Scedosporium prolificans).";
RL   G3 (Bethesda) 7:3831-3836(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKS06215.1}.
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DR   EMBL; NLAX01001034; PKS06215.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N3N1B2; -.
DR   STRING; 41688.A0A2N3N1B2; -.
DR   VEuPathDB; FungiDB:jhhlp_006961; -.
DR   InParanoid; A0A2N3N1B2; -.
DR   OrthoDB; 1788094at2759; -.
DR   Proteomes; UP000233524; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd08267; MDR1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR11695; ALCOHOL DEHYDROGENASE RELATED; 1.
DR   PANTHER; PTHR11695:SF649; PEPTIDASE; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233524}.
FT   DOMAIN          16..335
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   345 AA;  36876 MW;  0087312AD7A1638F CRC64;
     MVSHMKAWRY SVVHGKLEDS LVLSESVPAP ENSALAVDQL LIQVISAALN PVDYKLPEAP
     VVGRIMIKRP ATPGLDFAGR IVATHPNNKD FREGQLVFGG LSHSSQYGTL GQFIVAKSSE
     CALLPTGVNP DDAASVGTAG TSALQALPTA IVKPGAKVFI NGGSGGVGTW TVQFAKVLGA
     HIVTTCSTSN VSRCERLGAD EVIDYTKVDL VEELKRRGDV YDLIVDNVGN NPALYSNSNI
     LLKPGGSLIQ VGVGAGLSFK GIFASAAKQM AQYLPGARGY HFIQMDNNSK SFLQIGQWLV
     EGKVRAHVDT SFGWEDVPAA FRKLREGHVK DKLVIRIPNE SVIEE
//