ID   A0A2N3N8N9_9PEZI        Unreviewed;       357 AA.
AC   A0A2N3N8N9;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=jhhlp_004785 {ECO:0000313|EMBL:PKS08732.1};
OS   Lomentospora prolificans.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Microascales; Microascaceae; Lomentospora.
OX   NCBI_TaxID=41688 {ECO:0000313|EMBL:PKS08732.1, ECO:0000313|Proteomes:UP000233524};
RN   [1] {ECO:0000313|EMBL:PKS08732.1, ECO:0000313|Proteomes:UP000233524}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHH-5317 {ECO:0000313|EMBL:PKS08732.1,
RC   ECO:0000313|Proteomes:UP000233524};
RX   PubMed=28963165; DOI=10.1534/g3.117.300107;
RA   Luo R., Zimin A., Workman R., Fan Y., Pertea G., Grossman N., Wear M.P.,
RA   Jia B., Miller H., Casadevall A., Timp W., Zhang S.X., Salzberg S.L.;
RT   "First Draft Genome Sequence of the Pathogenic Fungus Lomentospora
RT   prolificans (Formerly Scedosporium prolificans).";
RL   G3 (Bethesda) 7:3831-3836(2017).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKS08732.1}.
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DR   EMBL; NLAX01000094; PKS08732.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N3N8N9; -.
DR   STRING; 41688.A0A2N3N8N9; -.
DR   VEuPathDB; FungiDB:jhhlp_004785; -.
DR   InParanoid; A0A2N3N8N9; -.
DR   OrthoDB; 2342072at2759; -.
DR   Proteomes; UP000233524; Unassembled WGS sequence.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42940; ALCOHOL DEHYDROGENASE 1-RELATED; 1.
DR   PANTHER; PTHR42940:SF8; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233524}.
FT   DOMAIN          33..134
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          186..305
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   357 AA;  38071 MW;  B43E30816BA58397 CRC64;
     MAPQMMKAAI CKEPGKPLVV EEIPVPEPTG RFILVKVKAA SLCHSDLGII DGTFGSLMMP
     LVVGHEAISI VEKLGPDAGG YGINVGDTVG ASLWHDSCLN CVDCKTAGAE FCKKMQIKGM
     TSPGCFSEYT LVDPVATVVV RKAEDKSDAP ISDLSPLFCA GITVWDAIER AKVRPGDSVA
     ILGVGGLGQM AARYATELGA KVFVLDVRDE QLNAAKSDGI ADETINIKML SPQELEDKVM
     ELNGGVLLDT AIVTTGVVPA YLSAMGIVRV AGHIIAVGLP HESIPLNSNV IAQRCFSITG
     AKVPGKKGIQ RCIDYSMKKN IRPKINDRKF VLEDINEMIA LMKAGEVDKG RMLVEFF
//