ID   A0A2N3N8Q5_9PEZI        Unreviewed;       847 AA.
AC   A0A2N3N8Q5;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   13-SEP-2023, entry version 18.
DE   RecName: Full=CDC45-like protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=jhhlp_003428 {ECO:0000313|EMBL:PKS08819.1};
OS   Lomentospora prolificans.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Microascales; Microascaceae; Lomentospora.
OX   NCBI_TaxID=41688 {ECO:0000313|EMBL:PKS08819.1, ECO:0000313|Proteomes:UP000233524};
RN   [1] {ECO:0000313|EMBL:PKS08819.1, ECO:0000313|Proteomes:UP000233524}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHH-5317 {ECO:0000313|EMBL:PKS08819.1,
RC   ECO:0000313|Proteomes:UP000233524};
RX   PubMed=28963165; DOI=10.1534/g3.117.300107;
RA   Luo R., Zimin A., Workman R., Fan Y., Pertea G., Grossman N., Wear M.P.,
RA   Jia B., Miller H., Casadevall A., Timp W., Zhang S.X., Salzberg S.L.;
RT   "First Draft Genome Sequence of the Pathogenic Fungus Lomentospora
RT   prolificans (Formerly Scedosporium prolificans).";
RL   G3 (Bethesda) 7:3831-3836(2017).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the CDC45 family.
CC       {ECO:0000256|ARBA:ARBA00010727}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKS08819.1}.
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DR   EMBL; NLAX01000010; PKS08819.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N3N8Q5; -.
DR   STRING; 41688.A0A2N3N8Q5; -.
DR   VEuPathDB; FungiDB:jhhlp_003428; -.
DR   InParanoid; A0A2N3N8Q5; -.
DR   OrthoDB; 1407079at2759; -.
DR   Proteomes; UP000233524; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   InterPro; IPR003874; CDC45.
DR   PANTHER; PTHR10507; CDC45-RELATED PROTEIN; 1.
DR   PANTHER; PTHR10507:SF0; CELL DIVISION CONTROL PROTEIN 45 HOMOLOG; 1.
DR   Pfam; PF02724; CDC45; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233524}.
FT   REGION          191..294
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          397..425
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          718..797
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        193..214
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        215..230
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..286
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        404..425
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        722..764
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        765..789
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   847 AA;  93604 MW;  C87A77B8500E2DA9 CRC64;
     MYLPRSLISK LYAHLQSTRH PLSPPVLILV ALEPDALCAC RILTRLFKHD YIQHKIQPIA
     GYSDLERAGE KLVQPMMESR GGSGGVVVCL GVGGMTDLAS LLGLEQEDGV FSGVEVWLLD
     AHRPWNLANV FGGFPVDPAA PEDEARFPAG AEGGRIERAY KPGKGGIIVF DDGDIEDDLQ
     TERDAYLTLL DMPEVADDEE DLGETDDESE GEEDELVRVG QKRKSWSDRE DDECSEEEDR
     PAQRRRSNSS SSIPESPRRP QGRGLISIRD QSAAVSSSTP TEPPSAAQGP SARALRRKFL
     RLRDEKETII QKYYRMGTSF SEPISSMMYS LASELGREDN DLLWLAIVGV TSMELYGRSS
     AGIAVPVRGN ERNRAAGWLG IRGARIRQLL RDEVRRLNPP DMTNGRVSPE NSGIIPTTAR
     SPEDTSIRLS PEPKFLLIRH WSLYDSMLHS PYLFSRLKTW SDTGLKRLHK LLAKMGVSLV
     QCKQSYTHMD MVLKRELRSK LLKYASLYNL DDMVPSVDTD GKDRGGAKDG WGFVRSWGWR
     ATLSAQDVGV VIGALLEVGK HTGDKTHGAS AGGASQIVEE SAADALASRS EEWVSRFWEA
     YDALDDIDAL KAGLPTAQFL HRAIYRTGTS LIQKKQIKHL RAFRLCVVKD GPDVALFNHP
     AALTKLALWI GEALLEQERE ATGKLSHGGR GTPLVVASLD EKQGLYVVVG TGGGGGPDTV
     FLDKEAAKRR KKEKEEKAKR READRKAREK IREEKRAARE AAGEDYDELE TESEGEDVSD
     SEAEDIDEDE GKEKGYGLNR FGTAFNDVIS ETGARVRVDS FEHCVVEVKK EDLGGFLENL
     SMKAVVG
//