ID A0A2N3NB05_9PEZI Unreviewed; 475 AA.
AC A0A2N3NB05;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 28-JUN-2023, entry version 16.
DE RecName: Full=CBF1-interacting co-repressor CIR N-terminal domain-containing protein {ECO:0000259|SMART:SM01083};
GN ORFNames=jhhlp_004222 {ECO:0000313|EMBL:PKS09604.1};
OS Lomentospora prolificans.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Microascaceae; Lomentospora.
OX NCBI_TaxID=41688 {ECO:0000313|EMBL:PKS09604.1, ECO:0000313|Proteomes:UP000233524};
RN [1] {ECO:0000313|EMBL:PKS09604.1, ECO:0000313|Proteomes:UP000233524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHH-5317 {ECO:0000313|EMBL:PKS09604.1,
RC ECO:0000313|Proteomes:UP000233524};
RX PubMed=28963165; DOI=10.1534/g3.117.300107;
RA Luo R., Zimin A., Workman R., Fan Y., Pertea G., Grossman N., Wear M.P.,
RA Jia B., Miller H., Casadevall A., Timp W., Zhang S.X., Salzberg S.L.;
RT "First Draft Genome Sequence of the Pathogenic Fungus Lomentospora
RT prolificans (Formerly Scedosporium prolificans).";
RL G3 (Bethesda) 7:3831-3836(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CWC25 family.
CC {ECO:0000256|ARBA:ARBA00006695}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKS09604.1}.
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DR EMBL; NLAX01000010; PKS09604.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N3NB05; -.
DR STRING; 41688.A0A2N3NB05; -.
DR VEuPathDB; FungiDB:jhhlp_004222; -.
DR InParanoid; A0A2N3NB05; -.
DR OrthoDB; 12277at2759; -.
DR Proteomes; UP000233524; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR019339; CIR_N_dom.
DR InterPro; IPR022209; CWC25.
DR PANTHER; PTHR16196; CELL CYCLE CONTROL PROTEIN CWF25; 1.
DR PANTHER; PTHR16196:SF0; PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG; 1.
DR Pfam; PF10197; Cir_N; 1.
DR Pfam; PF12542; CWC25; 1.
DR SMART; SM01083; Cir_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233524};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 10..46
FT /note="CBF1-interacting co-repressor CIR N-terminal"
FT /evidence="ECO:0000259|SMART:SM01083"
FT REGION 26..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 160..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..185
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..262
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..441
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 475 AA; 56290 MW; 603413308FBA60AB CRC64;
MGGDLNLKKS FHPGLLRNQK RVYEEEQRAL DERKRTQQRI NELKEERAKE EVQRQLEAAG
GQKRVDRVDW MYQGPTDGQM GTTEEREAYL LGKRRIDNLI KGTDHQKLEK NAGQESFMAM
QSANSAKDMA SKLSADPLMQ IKKQEQAAYE AMMNDPIKRK QLLASMGVKE GKDKEKDSDR
KKSRRRDERR DRHRSDRRRR DYSDDERERR RKRSDSGSRT RSPPRRRRTE GDGDGRRRRH
ESPERRRHRS PDARDKGSRR RSPSASRSRS PALRPKDKRH YRDRDDKRQN GHRDRRESLE
KENDHRSSGR RGDSPDDRRP EKENGDQSKD DRWRDRPRDG HPFVRANGDW RNDRRNDDRR
RNDWNGRRNH RGNGDFGEIP PRPREDKRAS DEDRARKLAE MQKAASELDR DREKRLAAVE
EQERRAKEED NRAREQAAKY GGDKRFINNV RQQANNLGLA ESMGRGRRGL QADED
//
