ID   A0A2N3NG64_9PEZI        Unreviewed;       597 AA.
AC   A0A2N3NG64;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=Adenosine deaminase domain-containing protein {ECO:0000259|Pfam:PF00962};
GN   ORFNames=jhhlp_003230 {ECO:0000313|EMBL:PKS11466.1};
OS   Lomentospora prolificans.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Microascales; Microascaceae; Lomentospora.
OX   NCBI_TaxID=41688 {ECO:0000313|EMBL:PKS11466.1, ECO:0000313|Proteomes:UP000233524};
RN   [1] {ECO:0000313|EMBL:PKS11466.1, ECO:0000313|Proteomes:UP000233524}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHH-5317 {ECO:0000313|EMBL:PKS11466.1,
RC   ECO:0000313|Proteomes:UP000233524};
RX   PubMed=28963165; DOI=10.1534/g3.117.300107;
RA   Luo R., Zimin A., Workman R., Fan Y., Pertea G., Grossman N., Wear M.P.,
RA   Jia B., Miller H., Casadevall A., Timp W., Zhang S.X., Salzberg S.L.;
RT   "First Draft Genome Sequence of the Pathogenic Fungus Lomentospora
RT   prolificans (Formerly Scedosporium prolificans).";
RL   G3 (Bethesda) 7:3831-3836(2017).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKS11466.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NLAX01000008; PKS11466.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N3NG64; -.
DR   STRING; 41688.A0A2N3NG64; -.
DR   VEuPathDB; FungiDB:jhhlp_003230; -.
DR   InParanoid; A0A2N3NG64; -.
DR   OrthoDB; 4403at2759; -.
DR   Proteomes; UP000233524; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409:SF37; A_DEAMINASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233524}.
FT   DOMAIN          277..557
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   597 AA;  68717 MW;  499957410B53682D CRC64;
     MAENNLEDLP NSKPAKRTRT MEQGLDYAQS APKSVEATAL LPQGTSTLTS DVYSGVEDYF
     SRRDEVENRQ RAMGFDHACT IKASRKEQTA NAIIQKLKQL DKQRVYDTAE PRVGFAGQRH
     PRLVGDHFLS NVELIDRTDL LRVAQRMPKG AHLHIHFNAC LLPDVLLGIA KTMNRMFITC
     DRPLLPDHDY LSYQACEIQF CLIPPERERP GNLFTTTYQP RQTMPFDRFL GEFSSHYPHA
     SADEWLMSKV VFDEEESHNK LQTCAGQVIS ATFRSLFNYE RAYRVYTRWL LEDFVRDNIQ
     YAEIRPNFME TNQLVTDDGT SMINNDGIMA IIIDEYRRFQ AQTKGYFGGL KIIYCTPRVF
     SRDKVRFALN ECIRFKKQWP EWIAGFDLVG EEAQPNPLKA FIPEFLEFRQ QCRKENLDIP
     FLFHCGETLD IGTDTDGNLI DALLLNAKRI GHGFALARHP YVMEKMKERG VCLELCPISN
     EVLGLTPRIN GHSMYTLLAN NVHCTVSSDN GTFFRSTLSH DFYQVMIGRA DMSLHGWRQL
     IEWSLQHSCM SDGERQGVWV QWEKRWEEFL DWMLVEYGAL VADGGVHATA DPMPKSE
//