ID A0A2N3NHJ0_9PEZI Unreviewed; 1817 AA.
AC A0A2N3NHJ0;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=U3 small nucleolar RNA-associated protein 10 {ECO:0000256|ARBA:ARBA00015399, ECO:0000256|RuleBase:RU367065};
GN ORFNames=jhhlp_001199 {ECO:0000313|EMBL:PKS11905.1};
OS Lomentospora prolificans.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Microascaceae; Lomentospora.
OX NCBI_TaxID=41688 {ECO:0000313|EMBL:PKS11905.1, ECO:0000313|Proteomes:UP000233524};
RN [1] {ECO:0000313|EMBL:PKS11905.1, ECO:0000313|Proteomes:UP000233524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHH-5317 {ECO:0000313|EMBL:PKS11905.1,
RC ECO:0000313|Proteomes:UP000233524};
RX PubMed=28963165; DOI=10.1534/g3.117.300107;
RA Luo R., Zimin A., Workman R., Fan Y., Pertea G., Grossman N., Wear M.P.,
RA Jia B., Miller H., Casadevall A., Timp W., Zhang S.X., Salzberg S.L.;
RT "First Draft Genome Sequence of the Pathogenic Fungus Lomentospora
RT prolificans (Formerly Scedosporium prolificans).";
RL G3 (Bethesda) 7:3831-3836(2017).
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC Involved in ribosome biosynthesis. {ECO:0000256|ARBA:ARBA00025076}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC {ECO:0000256|ARBA:ARBA00011399, ECO:0000256|RuleBase:RU367065}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU367065}.
CC -!- SIMILARITY: Belongs to the HEATR1/UTP10 family.
CC {ECO:0000256|ARBA:ARBA00010559, ECO:0000256|RuleBase:RU367065}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKS11905.1}.
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DR EMBL; NLAX01000004; PKS11905.1; -; Genomic_DNA.
DR STRING; 41688.A0A2N3NHJ0; -.
DR VEuPathDB; FungiDB:jhhlp_001199; -.
DR InParanoid; A0A2N3NHJ0; -.
DR OrthoDB; 5480100at2759; -.
DR Proteomes; UP000233524; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR012954; BP28_C_dom.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR022125; U3snoRNP10_N.
DR InterPro; IPR040191; UTP10.
DR PANTHER; PTHR13457; BAP28; 1.
DR PANTHER; PTHR13457:SF1; HEAT REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF08146; BP28CT; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF12397; U3snoRNP10; 1.
DR SMART; SM01036; BP28CT; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU367065};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367065};
KW Reference proteome {ECO:0000313|Proteomes:UP000233524};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU367065};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|RuleBase:RU367065};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552,
KW ECO:0000256|RuleBase:RU367065};
KW Transmembrane {ECO:0000256|RuleBase:RU367065};
KW Transmembrane helix {ECO:0000256|RuleBase:RU367065}.
FT TRANSMEM 133..155
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367065"
FT REPEAT 592..629
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 1533..1687
FT /note="BP28 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01036"
FT REGION 466..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 887..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..486
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1817 AA; 200482 MW; 93FE4E317B9BDDEE CRC64;
MATSLAKQLA QIAAKSKTTL NAKAQKAAHS KSLIWEPKVA ATQSFQSLYP VCYEGFEELC
GLDARFTTFR ATLFSEQSQS EDRTQLTEAE NAELDRRVET FLRLVGSRLR LMPAIKAIEW
LIRRFRIHEF NTAFLLTTFL PYHTLPVFVT LLSILPSQIP DDYRFLQPYI RSLTSPPRAT
LVHQTINHPR LLAAISEYTL ASCNAKQHYQ TLIAFWGGIL TEAVNGLVDK NKSGRKAVQY
DNDQALLHQL GPIFGEALMM KKVPQAQIAA YMALAVFVSK GDLGDAAVSA FMEQLALGWT
SETVRPGLVC LSILGQHRSA KQVSGKIAKA LLKIPDVEKH LVEIGREWRV DRLANGLCLA
MIDRAARKGC ARGLHVVGAL IRANVLTSKQ TSVLFKALLL LGTNLSEDVD KSGSVRKELG
TMLVQLSQDP GECGDIIQSA ITDIDFDMDQ LEMRLDLSLR QNKALPSTEE GAMEKDETVE
PAKENPTDEL AKLARLPSGL SANLGRDAGA AFPAVSQAFL RAIIDPSSEK LLQDFDALPI
LSRDQALVDP TYFAFYVRIW CGAFPALAKA KALEMVKLRL KACDQGVDLQ GLIPYILTGL
SDPSKKVRQA AANLLTVLAQ AYPSDTKESG TTVWATKTLY PGSQNREDLG TEAAIKVIKS
VLLPALEECV IHQDHVSSIF ESSIGPGKAK DSEETKGRLP PPVRLAFAKF ISNAVFRTPF
LLVKERLLKA LNRVRSIPST SRTQLLLPSL NWWAGLTSQE VSELVKKERV DEADLNQRFV
ETVVANDTAG LQALLKIIIT SKDTREDFVE AIFLRLRKLW SLMKPENKSS LANQMIDLAL
SGSDDDDMPR SKSIEAAELL RNVELTTEIL SHFLESIHME TNIVVDSPPN KRRRLSNEGA
RGSGLQPSPE ITAALKKATF VLQLIEISDP AAHAALLPSL FSTLAKLQTF RSVVGSDLGY
LQNVVLTSLH AMLPAYKANS ELKITISDGY GDLLVNCIQK SSSPIVQNAA LLLIASLATT
APDVVIHCVM PIFTFMGVSV IRQSDDYSAH VVNQVIKEVV PPLVATLRKG KRSVVAASSE
LLLSFTSSYE HIPSHRRFGI FMSLVDTLGP DEFLFAIIAL LVEKQGPTDG VLGFVTELLD
RHNVRTQLDT LVKLIRLIGD LFKPAPNLAS ALLRPTSKLD PQVSQEAALN QLSALPALLS
SRRLRIQVRK ITERDDMQAS EVRELYAGLL ENILSLADVV KIHKELYALC GESLASLLNL
LTIGEFIKAV ENLLDRSDLG LRQKVLKALE TRVNQESSAD PSSRIVLLGF LPQLTAAIRD
SEDIRYKHTA VACVDKIAEK YGEKDLEAVA AAASIIAGEH CLGQSDRHLR VMALLCLASL
VSVLGHGVIP VLPSASKYAM NYLRECMTEK EPDSELHNAC YFFVLSVVQH MPEMITGSYF
EQILAISNAS AEQELDDEAE DSRRTCLKAL ATQIDSKTLF TGLANGWPRA AGAGFKVGFH
SFSEFCRSFI DMLIQAIGEY IDLIRTAITS HREQIIRKNV ASLSSIFLNA HDFRRQEFEK
GPVTDAVATK VAEIEGSINE VALLMIHKLN DGTFRPIFSQ LIDWTGTGLA KSDITGRFRR
SQSVYGFLYA FFNQLGRIVT SYATYMLDDA VRILKLASPK ESREARILWE SVLKVLAKCF
EHDEDGFWQT PAHFGAVAPV LVDQFRYSGT LDLSESLAPA IVELARAASS QAHQKELNTS
ILKLLRSEQA SARLAAVKCQ QALADRLGEE WLAMLPEMLP FISELQDDDD EIVERETHRW
IVKIEGVLGE SLDNMLQ
//
