ID   A0A2N3NK61_9PEZI        Unreviewed;      1460 AA.
AC   A0A2N3NK61;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Protein CFT1 {ECO:0000256|ARBA:ARBA00039443};
DE   AltName: Full=Cleavage factor two protein 1 {ECO:0000256|ARBA:ARBA00041264};
DE   AltName: Full=Protein cft1 {ECO:0000256|ARBA:ARBA00039187};
GN   ORFNames=jhhlp_001015 {ECO:0000313|EMBL:PKS12804.1};
OS   Lomentospora prolificans.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Microascales; Microascaceae; Lomentospora.
OX   NCBI_TaxID=41688 {ECO:0000313|EMBL:PKS12804.1, ECO:0000313|Proteomes:UP000233524};
RN   [1] {ECO:0000313|EMBL:PKS12804.1, ECO:0000313|Proteomes:UP000233524}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHH-5317 {ECO:0000313|EMBL:PKS12804.1,
RC   ECO:0000313|Proteomes:UP000233524};
RX   PubMed=28963165; DOI=10.1534/g3.117.300107;
RA   Luo R., Zimin A., Workman R., Fan Y., Pertea G., Grossman N., Wear M.P.,
RA   Jia B., Miller H., Casadevall A., Timp W., Zhang S.X., Salzberg S.L.;
RT   "First Draft Genome Sequence of the Pathogenic Fungus Lomentospora
RT   prolificans (Formerly Scedosporium prolificans).";
RL   G3 (Bethesda) 7:3831-3836(2017).
CC   -!- SIMILARITY: Belongs to the CFT1 family.
CC       {ECO:0000256|ARBA:ARBA00038304}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKS12804.1}.
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DR   EMBL; NLAX01000003; PKS12804.1; -; Genomic_DNA.
DR   STRING; 41688.A0A2N3NK61; -.
DR   VEuPathDB; FungiDB:jhhlp_001015; -.
DR   InParanoid; A0A2N3NK61; -.
DR   OrthoDB; 149432at2759; -.
DR   Proteomes; UP000233524; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR   InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR10644:SF2; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1; 1.
DR   PANTHER; PTHR10644; DNA REPAIR/RNA PROCESSING CPSF FAMILY; 1.
DR   Pfam; PF03178; CPSF_A; 1.
DR   Pfam; PF10433; MMS1_N; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233524}.
FT   DOMAIN          146..771
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10433"
FT   DOMAIN          1077..1422
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03178"
FT   REGION          508..537
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        518..534
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1460 AA;  158832 MW;  04F8BB0DEBE46005 CRC64;
     MFIVRSTEGL HGNFWPGSKM QCYTELTAPT AVTHSLTLPF LSQDSSSLVV AKGSLLQVFT
     TKSIPAEVDN AQRQQSPSIV PPALAFESRR SDDDGLDSSL LAEGIHRTDR GNNTKLVLIA
     EYPLAGTVVG LAAVNMQGSR SGGHGLLVAL RTAKACLVQW NPDTQTIIDT SVHFYENEDG
     ASFDLPLSEY ETVLQADPGS RCAAMKFGLR SLAILPFKQA SADIEMDDWD VDLDGPRPVK
     EAAAESTDKT TGINGTKEKP YTESFVLRFP QLDPTLLYPE HFAFLYEYRE PTFGILSSTQ
     QPGYFFGRKD HKSYKVFTLD LHQRASTTIL AVDNLPHDVH RVLPLPAPVG GALLVGDNEL
     IHIDQSGRAN GVGLNPFAKV CTSFPLADQS SLHLQLEHCV IEQLAPESGE LLMVLNTGNM
     AIVSFKIDGR TVTGVNVRMV SPECGGSIIP SRISCISKVD KQALFVGSTT SDSLVVGWTR
     KHSQSTRRKS RLVDPSLEYE LDDLDIEDDE DEDDLYGDST SPTSTGNQDG TNGQAKDGDL
     IFRVQDTLLS IAPIREFSSG RAAFFPDSEE QRNSEGVVSP LQLACAVGRG NAGAIAILNK
     DIQPKVIGRF EFPEARGFWT MSVQKPIPKG LQAEKDISAA LGSDYGAAAE FDRFMIVAKI
     DLDGYETSDV YAVTAAGFEA LTGTEFDPAA GFTIEAGSMG NYKRVIQVLK SEVRCYDGDL
     GLSQIIPMLD EETGADPRVV SGSIADPFLL LIRDDSSVWM AQIDKNCELE EMERLDKTLV
     SSKWLTGCLY SDSEGHFTKD RKETSSPNIL AFLVNTAGAL YVYSLPDLSK PIFVAEGLAY
     LPTFLSSDFS IRRGTPKESL TEVLVTDLGD TTQKSPYLIV RNSTDDLTIY QPILRQGIES
     YGKALHFKKL RNPTLAANPD IPPPQDDTAP QEPRFVPLRA CANVGGYSTV FLPGVSPSFL
     IKSSKSTPKL IGLQGRGVRG MSSFHTEGCE RGFIYADSEG IARVTQLPSK TSFAELGISV
     CKVEMGFNVK QIAYHAAMET YTVGGSILEP FELPKDDEHR KEWARENIDM KPMVERGQVK
     LINPVNWAVI QTIDFEPYED ILCLKALNLE VSEVTKERRQ LIVVGTGTRK GEDLPIRGRV
     YVYDVVAVIP EAGKPETNKR LKLIAKEDIP RGAVTSVSEI GTQGLMLVAQ GQKCMVRGLK
     EDGSLLPVAF MDMSCYVTAA KELRASGLCV MADAAKGLWF TGCTEEPYRM QLFGKSTTNL
     EVVTADFLPD GKNLYLIAAD MNGDIHVLQY DPEHPKSLQG HLLLHKTTFC TASNGPTVTL
     LLPRTVTSSS GLQQNGHESG TFHNHILLLA SESGMLSAIT PLSEAAYRRL LSLSAQLVTA
     LPTAAGTNPK AYRMPHPSAG SVGVDTASGR TMIDGAVLAR WCELGTGRRA ELAGKTGYSG
     VDQVRGELDS LLGWTGLAYY
//