ID A0A2N3XSR0_SACSN Unreviewed; 322 AA.
AC A0A2N3XSR0;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:PKW13689.1};
GN ORFNames=A8926_1237 {ECO:0000313|EMBL:PKW13689.1};
OS Saccharopolyspora spinosa.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=60894 {ECO:0000313|EMBL:PKW13689.1, ECO:0000313|Proteomes:UP000233786};
RN [1] {ECO:0000313|EMBL:PKW13689.1, ECO:0000313|Proteomes:UP000233786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44228 {ECO:0000313|EMBL:PKW13689.1,
RC ECO:0000313|Proteomes:UP000233786};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 Actinobacteria strains.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKW13689.1}.
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DR EMBL; PJNB01000001; PKW13689.1; -; Genomic_DNA.
DR RefSeq; WP_029535524.1; NZ_PJNB01000001.1.
DR AlphaFoldDB; A0A2N3XSR0; -.
DR STRING; 994479.GCA_000194155_03956; -.
DR OrthoDB; 9802008at2; -.
DR Proteomes; UP000233786; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 2..285
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 322 AA; 32454 MW; 019B6C0F5D8C6DE1 CRC64;
MRAVCVIGLG LIGGSVLRAA KAAGRPAWGT TRSESDVAAA RADGFDILDI GPTLRRAAEE
DALVVVATPL TAVRDVLREV AEHAPEAWLT DAVSVKGPVA AEVRSLLPGA RYAGGHPMAG
VSGSGWSVGS GELFAGAAWA VTAEEDTTLA AWREAAQLAL DCGAQVVPTS AASHDFAVAR
ISHLPHVFAA VLASVGADGG PLALSLAASS FRDGTRVAGT APELVRAMTE GNRIALLDAV
DDALGRLGAA RGSLASTGGL KSTVDAGHDA RQTLDELATA ARASATVQLN GTALERLREL
GERGGRVVAL SAEAAAVELP VA
//
