ID   A0A2N3XYJ3_SACSN        Unreviewed;       831 AA.
AC   A0A2N3XYJ3;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Putative flippase GtrA {ECO:0000313|EMBL:PKW15699.1};
GN   ORFNames=A8926_3447 {ECO:0000313|EMBL:PKW15699.1};
OS   Saccharopolyspora spinosa.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=60894 {ECO:0000313|EMBL:PKW15699.1, ECO:0000313|Proteomes:UP000233786};
RN   [1] {ECO:0000313|EMBL:PKW15699.1, ECO:0000313|Proteomes:UP000233786}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44228 {ECO:0000313|EMBL:PKW15699.1,
RC   ECO:0000313|Proteomes:UP000233786};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 Actinobacteria strains.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the GtrA family.
CC       {ECO:0000256|ARBA:ARBA00009399}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKW15699.1}.
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DR   EMBL; PJNB01000001; PKW15699.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N3XYJ3; -.
DR   STRING; 994479.GCA_000194155_03771; -.
DR   OrthoDB; 3752109at2; -.
DR   Proteomes; UP000233786; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR   InterPro; IPR007267; GtrA_DPMS_TM.
DR   PANTHER; PTHR38459; PROPHAGE BACTOPRENOL-LINKED GLUCOSE TRANSLOCASE HOMOLOG; 1.
DR   PANTHER; PTHR38459:SF1; PROPHAGE BACTOPRENOL-LINKED GLUCOSE TRANSLOCASE HOMOLOG; 1.
DR   Pfam; PF04138; GtrA; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        69..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        101..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        134..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        256..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        305..333
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        345..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        410..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        442..463
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        469..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        498..518
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        524..541
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        548..567
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        802..823
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          12..121
FT                   /note="GtrA/DPMS transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF04138"
SQ   SEQUENCE   831 AA;  90130 MW;  24B6634C90B312CF CRC64;
     MWCKTSRSEL LRFALVGGAN TAVHCSVYLA LWLLVPYLLA HLVATVAATL CSYLLNCRFT
     FEVAPNRRTL LLFPLSNLAV IGLSTAVVAV SVAVFDVDSR LAPVAAGLVV VPVTFLLSRA
     VLTERLPLLE WRGAVGVGVA VALLSQVPVL VNPSFYFWDD SAAQFLPMWH RLGERLLAGD
     WPLGLDLDSW MGGNLAAESL FGIWNPVHLL DCLLVVWLGD LAIGAAVVKT QFLVTLGAGT
     FLLCRCYGAG RGISSVLAVA LPLSGFVLYF QAATWAGGLM GFAWLPWAWW ALRRVLDGRL
     PVFVTWMLCY LCVSAGDPYG VLALGAVFAG LLAETGRNWS RIRRLVLVGV AVGASLPLIF
     FPVLETSAVG WRSGHELFNI GQLVPGIGDL LNASTPSFVP QILSFGSFRM SVPATYFAWF
     AVPLLAWLDW RSAGGLWRRC RCAALIAGGY FLLCLGPSNV WLFRWPLRHV VVLHLAVAVL
     LAVSLSRGLR TDHFKVRLAC SAGTVLLGGY LSFAAWPALA PKHLVSLAVI TVLLAAVLIL
     HRKQLMAAVL HLGTACALAL QMLWFPANRD VAVYNFPTSI AELRTRYAEF HGGTVLQIAD
     RTLIPPDDVA SRSAWKHLLF GNMHAAAGVA SLVSYTGIGH DALHTRLCLS YYGATCPQAY
     DRLWQPDGLV DRLKVTHVVV QRRLREVPEA PAGWQVTRRD ADVVVLKRET ALPWPAGRLS
     ASRGVRVLDD RQHGQRHETV RFGRTADRAE LVFARLAWPG YQATVDGRRV PVVGTDAGLL
     TVRLPPGLTG GTLALSWSPP GFALHLLLAC TGALLALALS VAAPQPGRRT R
//