ID A0A2N3Y8W8_SACSN Unreviewed; 762 AA.
AC A0A2N3Y8W8;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=DNA helicase IV {ECO:0000313|EMBL:PKW19335.1};
GN ORFNames=A8926_7501 {ECO:0000313|EMBL:PKW19335.1};
OS Saccharopolyspora spinosa.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=60894 {ECO:0000313|EMBL:PKW19335.1, ECO:0000313|Proteomes:UP000233786};
RN [1] {ECO:0000313|EMBL:PKW19335.1, ECO:0000313|Proteomes:UP000233786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44228 {ECO:0000313|EMBL:PKW19335.1,
RC ECO:0000313|Proteomes:UP000233786};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 Actinobacteria strains.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKW19335.1}.
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DR EMBL; PJNB01000001; PKW19335.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N3Y8W8; -.
DR STRING; 994479.GCA_000194155_00665; -.
DR OrthoDB; 9787585at2; -.
DR Proteomes; UP000233786; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 190..604
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 211..218
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 762 AA; 84820 MW; 5178832595C32C2F CRC64;
MSNARVDRDT VRAQEITAEQ QYLSMLYAKL DALRQETTQR LKETLRASGG TPQARTERDI
STRMYTDKLT QLSAVEHGMC FGRLDLDSGE TFHVGRLGLF DEDHEYEPLL VDWRAPAARP
FYLATAAARD GVGRRRHLRT SWRKVLDYED EVLDLDAAEQ GSDLGLAGEA TLLARLDARR
TGQMQDIVAT IQGEQDRIIR AGMNGVLVVQ GGPGTGKTAV ALHRAAYLLY TFREQLSKRG
VLVVGPNPTF LRYIGQVLPS LGETGVLLST AGGLYPGITA TGEESARTAE IKGRASMVDV
LAAAVRDRQQ VPADYTELTF DHEALRIDRR TATQARTRAR RSRRPHNLAR RIFRNEMFSA
LTLQVADRLG RDLLDRRDLD DINRELRADA VVSKALDELW PEITPQELLD DLLCSPERLA
TATRKHLDDD ERDELLRLPG TTWTPADVPL LDELAELLGA DDAQERAERE HQQREELAYA
QGVLHIMEQD EELADEERLR VSDVLDAELL AERFRSTSDL TAAERAAEDR TWTFGHVIVD
EAQELSPMAW RVLMRRCPSR SMTLVGDVAQ TGALAGANSW HDVLHPYVQD RWKLVELTIN
YRTPAEIMAI AADVLSEMDT DLVVPRSVRT SGHRPWTRRL PSDGLATELP AMIIDELHEV
GDGRLAVLMP PELLAGIGPR LAESLPDAAI GTRPDDLESP CVLLTVDQAK GLEFDSVLVV
DPATIVAESE RGLNDLYVAL TRATQRLGVV HPDELPAVLR GM
//
