ID A0A2N4SB33_9BACT Unreviewed; 505 AA.
AC A0A2N4SB33;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Potassium/proton antiporter {ECO:0000313|EMBL:PLB87305.1};
GN ORFNames=C0T31_01615 {ECO:0000313|EMBL:PLB87305.1};
OS Dysgonamonadaceae bacterium.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Dysgonomonadaceae.
OX NCBI_TaxID=2065189 {ECO:0000313|EMBL:PLB87305.1, ECO:0000313|Proteomes:UP000234415};
RN [1] {ECO:0000313|EMBL:PLB87305.1, ECO:0000313|Proteomes:UP000234415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XHS2771 {ECO:0000313|EMBL:PLB87305.1,
RC ECO:0000313|Proteomes:UP000234415};
RA Vasudevan G., Joshi A.J., Hivarkar S., Lanjekar V.B., Engineer A.S.,
RA Dhakephalkar P.K., Dagar S.;
RT "Anaerobic cellulose degrading bacterium isolated from hot springs that can
RT be used for biotechnological applications.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLB87305.1}.
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DR EMBL; PKMK01000002; PLB87305.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N4SB33; -.
DR OrthoDB; 9810759at2; -.
DR Proteomes; UP000234415; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR PANTHER; PTHR32507:SF7; K(+)_H(+) ANTIPORTER NHAP2; 1.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR PROSITE; PS51202; RCK_C; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000234415};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 30..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 414..496
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 505 AA; 55532 MW; C4F68755BE5DF736 CRC64;
MTVISTEFLL LIGSLLFFVS LVVGKAGHKL GVPVLLLFLV VGMLFGSDGF GLNFQNVQIA
QTIGTICLCI ILFSGGLDTK FHEIKPIIAP GIVMSTVGVI LTALFTGLFV WFKFGHLFSA
VGAGLFTCFL LAATVSSTDS ASVFGILRSR GLNLKNNLRP LLELESGSND PMAYMLTIVL
MSIIQSGDHP SFLSVTGLIV MQLTIGAIVG FLMGKISVRI MNGIRMDNPS LYPVLLLVLG
VFSFSSTYFL KGNGYLAVYI TGLVLGNSKF PQRRSSMKFM DGFAWMSQIL LFLTLGLLVN
PRELLTVLIP ALVIAFFVIF VARPLSIFLS LAPFRNIHFK DKIFVSWVGL RGAVPILFSI
LPLASGIAGA RIIFNIVFVI TIVSLLFQGT TLSLVAKCLG VSEKPKYFRK IEEFDVEFSE
DIKSAMTEIN ITKETLKHGR NLIELPFPER TLVVMVKRGD HYFVPTGKTE LHEGDILLVI
SDDDEALHET YRQLGILDYS FQKNK
//
