ID A0A2N4UF72_9BURK Unreviewed; 976 AA.
AC A0A2N4UF72;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Monovalent cation/H+ antiporter subunit A {ECO:0000313|EMBL:PLC53645.1};
GN ORFNames=CR155_12595 {ECO:0000313|EMBL:PLC53645.1};
OS Pollutimonas nitritireducens.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Pollutimonas.
OX NCBI_TaxID=2045209 {ECO:0000313|EMBL:PLC53645.1, ECO:0000313|Proteomes:UP000234328};
RN [1] {ECO:0000313|EMBL:PLC53645.1, ECO:0000313|Proteomes:UP000234328}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JR1/69-2-13 {ECO:0000313|EMBL:PLC53645.1,
RC ECO:0000313|Proteomes:UP000234328};
RA Grouzdev D.S., Tourova T.P., Goeva M.A., Babich T.L., Sokolova D.S.,
RA Abdullin R., Poltaraus A.B., Toshchakov S.V., Nazina T.N.;
RT "Two draft genome sequences of Pusillimonas sp. strains isolated from a
RT nitrate- and radionuclide-contaminated groundwater in Russia.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLC53645.1}.
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DR EMBL; PDNV01000007; PLC53645.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N4UF72; -.
DR OrthoDB; 9811798at2; -.
DR Proteomes; UP000234328; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR007182; MnhB.
DR InterPro; IPR025383; MrpA_C/MbhD.
DR InterPro; IPR046806; MrpA_C/MbhE.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR43373:SF1; ANTIPORTER SUBUNIT MNHA2-RELATED; 1.
DR PANTHER; PTHR43373; NA(+)/H(+) ANTIPORTER SUBUNIT; 1.
DR Pfam; PF13244; MbhD; 1.
DR Pfam; PF20501; MbhE; 1.
DR Pfam; PF04039; MnhB; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000234328};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 76..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 504..523
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 573..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 605..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 629..649
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..676
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 702..720
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 758..776
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 821..840
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 852..873
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 885..903
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 923..950
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..110
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 126..409
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
FT DOMAIN 616..677
FT /note="MrpA C-terminal/MbhD"
FT /evidence="ECO:0000259|Pfam:PF13244"
FT DOMAIN 696..791
FT /note="MrpA C-terminal/MbhE"
FT /evidence="ECO:0000259|Pfam:PF20501"
FT DOMAIN 823..944
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 976 AA; 105272 MW; 36F16BBD8A82DDD8 CRC64;
MLLALILVLP FAGSIIAALL PANARNLEAW LAGSVAIFSA VLVAWHLPDV IDGNVVKTTV
PWIPSLGVDL TLRMDGYAWL FAMIITTMGA LIVLYARYYL SPQDPVPRFF AFFQAFMGSM
LGVVLSGNLI QLVVFWELTS LSSFMLIAYW HHRLDARRGA RMALIITGAG GLCLLGGMLM
LGHVVGSYDL DVVLASGDLI RNHPWYTIML VLVALGALTK SAQFPFHVWL PNAMAAPTPV
SAYLHSATMV KAGVFLLARF WPVLAGTPEW AWIIGGAGLC SLILGAYAAT FQLDMKGVLA
YSTISHLGLI TLLLGMNSNL ALVAAVFHMI NHATFKASLF MAAGVVDHET GTRDLTRLSG
LYRSMPITAT LAVVAAASMA GVPLLNGFIS KEMFFAETVF VSGDWFSSYG LPIAAVVASA
FSVAYSLRFI MQVFFGPEPR DLPRAPHEPQ LLMLIPSGIL VLICLVVGIM PSVTLGPFLH
SATVAILGAD TPQYDLRVWH GLNLPLAMSF LAMVGGVGIL WLLRHRHRTR PGKTPLIYRF
DGRHTFESML EGLDVLASFL LDWARSPRLQ PQLLLVVVST FVVAMLPLLG GSWLQPEFTT
PINPYFVLMW VAGGACAVGA ANQAKYHRAA SLLMAGGAGL ATALTFAWMS APDLALTQLA
VEVVTTVLIL LGLRWLPPRV MTQDELPVQN VVRAFIRRFR DLIIAVVTGT GLSAVAYAVL
TRAHPEGISS FFVEQSLPMG GGANVVNVIL VDFRGFDTFG EITVLAIVAL TVYALLRRFR
PPPESMTLPN ARTILPANGK LLDHFAEPDP KALIPEGVMK LPAVLVRLLL PLATLISLYF
LLRGHNLPGG GFVGGLIMAT AIILQYVVGG VIWVEARQSL HPQNLIAIGL LLAAAAAMGV
WWASKPFLSA VSWDISLPVI GHLHLSTVLL FDLGVYLLVV GATVLILVAL AHQSLRLHRK
HSQAIVPPIS PEQGAH
//
