ID A0A2N4UHP7_9BURK Unreviewed; 367 AA.
AC A0A2N4UHP7;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:PLC54485.1};
GN ORFNames=CR155_06835 {ECO:0000313|EMBL:PLC54485.1};
OS Pollutimonas nitritireducens.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Pollutimonas.
OX NCBI_TaxID=2045209 {ECO:0000313|EMBL:PLC54485.1, ECO:0000313|Proteomes:UP000234328};
RN [1] {ECO:0000313|EMBL:PLC54485.1, ECO:0000313|Proteomes:UP000234328}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JR1/69-2-13 {ECO:0000313|EMBL:PLC54485.1,
RC ECO:0000313|Proteomes:UP000234328};
RA Grouzdev D.S., Tourova T.P., Goeva M.A., Babich T.L., Sokolova D.S.,
RA Abdullin R., Poltaraus A.B., Toshchakov S.V., Nazina T.N.;
RT "Two draft genome sequences of Pusillimonas sp. strains isolated from a
RT nitrate- and radionuclide-contaminated groundwater in Russia.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLC54485.1}.
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DR EMBL; PDNV01000004; PLC54485.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N4UHP7; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000234328; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000234328}.
FT DOMAIN 272..366
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 230..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 367 AA; 41585 MW; AB15CDC36EC144A8 CRC64;
MKPAVSPDKM VPVTILTGFL GAGKTTLLKR ILSEYHGRRI AVIENEFGPE SIDNELLVQD
SEEEIIELSN GCVCCTVRGD LMRTMNELRV KRQAGELNFE RVIIETTGMA NPGPVCQTFF
MDDEIAEYYR LDAVITVVDA KHGMETLDKQ EEAQKQVGFA DRILISKKDL VNDVDYQALR
ARLVRINPRA SITPVDFGVT DLKVLLDISG FNLNTILDID PDFLLDEHPD AAHDHDHSHG
HEHHEHEHEH EGDCNDHCGH QNHHHAHHDD EIGAFVFRSK KAFDPERLEE FLGGIVQVYG
PDLLRYKGIL YLKGINRRML FQGVHMMMGA EPGKPWLSGE KPNTKMVFIG RKLPQEIFTR
GLEQCLV
//
