ID   A0A2N4X278_9SPHN        Unreviewed;       416 AA.
AC   A0A2N4X278;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 10.
DE   SubName: Full=MBL fold metallo-hydrolase {ECO:0000313|EMBL:PLK26627.1};
GN   ORFNames=C0V78_06815 {ECO:0000313|EMBL:PLK26627.1};
OS   Novosphingobium sp. TH158.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Novosphingobium.
OX   NCBI_TaxID=2067455 {ECO:0000313|EMBL:PLK26627.1, ECO:0000313|Proteomes:UP000234499};
RN   [1] {ECO:0000313|EMBL:PLK26627.1, ECO:0000313|Proteomes:UP000234499}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TH158 {ECO:0000313|EMBL:PLK26627.1,
RC   ECO:0000313|Proteomes:UP000234499};
RA   Cai h.;
RT   "genomes of bacteria within cyanobacterial aggregates.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PLK26627.1}.
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DR   EMBL; PKRT01000001; PLK26627.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N4X278; -.
DR   OrthoDB; 9815874at2; -.
DR   Proteomes; UP000234499; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   Gene3D; 1.25.40.880; Alkyl sulfatase, dimerisation domain; 1.
DR   Gene3D; 3.60.15.30; Metallo-beta-lactamase domain; 1.
DR   InterPro; IPR038536; Alkyl/aryl-sulf_dimr_sf.
DR   InterPro; IPR029228; Alkyl_sulf_dimr.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   PANTHER; PTHR43223; ALKYL/ARYL-SULFATASE; 1.
DR   PANTHER; PTHR43223:SF2; LACTAMASE_B DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF14863; Alkyl_sulf_dimr; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:PLK26627.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000234499}.
FT   DOMAIN          39..240
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   416 AA;  46293 MW;  ACBAE5ACFE6D1139 CRC64;
     MNQPNSPDQN LRAAQMIRSG EGQSEAIDRG NGIWESRGVG NSYLVTTGDG DVLVNAGTLA
     DARRSRGLFA KVSSQPIRKI VLTQSHANQY GGLEIFKTSS NEVLAHRLYP EERRWNEALS
     EHYRRGSRRI FGGITGRTED MVPTAEVSPD VLLGDEGTQF TLGGRRFEVI WTPGGETRSA
     VIVWLPQERV AIVGNLFGPL FANHPNLNTL RGDKPRSAME FVASIRKLRD LRPVQILTGH
     EDIRGEEHIR KEVGRIADAV QWVHDRTLEG MNQGKDLRSL MREIRTPPEL TLTEEYGKLS
     WNVRAIWHEY TGWFDPARGT TELYDVPPES IGPALAELAG GAARLAERAQ AFLKTGQPLE
     ALHLVDMALA AEPDCLPAKQ AKRDALILLD HQTGGRNLWE RRWIAAQIRD LGLADA
//