ID   A0A2N4XI89_9BACT        Unreviewed;       458 AA.
AC   A0A2N4XI89;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=Multidrug-efflux transporter {ECO:0000256|ARBA:ARBA00031636};
GN   ORFNames=C0V77_01770 {ECO:0000313|EMBL:PLK46100.1};
OS   Emticicia sp. TH156.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC   Emticicia.
OX   NCBI_TaxID=2067454 {ECO:0000313|EMBL:PLK46100.1, ECO:0000313|Proteomes:UP000234203};
RN   [1] {ECO:0000313|EMBL:PLK46100.1, ECO:0000313|Proteomes:UP000234203}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TH156 {ECO:0000313|EMBL:PLK46100.1,
RC   ECO:0000313|Proteomes:UP000234203};
RA   Cai h.;
RT   "genomes of bacteria within cyanobacterial aggregates.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PLK46100.1}.
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DR   EMBL; PKRS01000001; PLK46100.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N4XI89; -.
DR   OrthoDB; 9776324at2; -.
DR   Proteomes; UP000234203; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR   CDD; cd13139; MATE_like_14; 1.
DR   InterPro; IPR002528; MATE_fam.
DR   InterPro; IPR048279; MdtK-like.
DR   NCBIfam; TIGR00797; matE; 1.
DR   PANTHER; PTHR43298:SF2; FMN_FAD EXPORTER YEEO-RELATED; 1.
DR   PANTHER; PTHR43298; MULTIDRUG RESISTANCE PROTEIN NORM-RELATED; 1.
DR   Pfam; PF01554; MatE; 2.
DR   PIRSF; PIRSF006603; DinF; 1.
PE   4: Predicted;
KW   Antiport {ECO:0000256|ARBA:ARBA00022449};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000234203};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        27..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        74..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        103..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        148..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        247..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        283..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        331..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        365..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        400..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        428..448
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   458 AA;  49302 MW;  7434BE5423656941 CRC64;
     MRKFFKLLIQ AIRGEEQNYT ELNINRAIFL LSVPMILEMV GESLFAIVDA FFVARYVGVE
     GVATVGLTES VLTLIYSVAI GLSTAATAIV ARRVGEGNKK GAGVAMAQVI IISLIFGVAV
     GILGFTFAED ILRLMGGDAH LIEKGAGFTR IIFASSPSII LLYTLSGALR GAGDASTAMR
     SIILANFINI GMDTLLIPVL GFGVEGAAIA TSIGRTIGVI YQLYAIFKGN GNMQIDRDQF
     KPNTEIIRSL INIAAGGTGQ FLIQSASWIF LTRILSSFGS DVVAGYTIAI RIIVFTILPS
     WGMSNAASTL VGQNLGAGKP DRAEKSVWRT ALYNMGFLLL VGIIFSVFAR EFIGIFNDNP
     KVIEVGVLCL QIICLGYVFF GFGMVIGQSL NGAGDTKTPT IMNLICFWAL EIPLAYLFAI
     TFKWGPSGVF WSIAISESVL AVIAIFVFRR GKWKTMQV
//