ID A0A2N5I2L6_9BACI Unreviewed; 312 AA.
AC A0A2N5I2L6;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=MurR/RpiR family transcriptional regulator {ECO:0008006|Google:ProtNLM};
GN ORFNames=CVD28_19450 {ECO:0000313|EMBL:PLS16214.1};
OS Bacillus sp. M6-12.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=2054166 {ECO:0000313|EMBL:PLS16214.1, ECO:0000313|Proteomes:UP000234907};
RN [1] {ECO:0000313|EMBL:PLS16214.1, ECO:0000313|Proteomes:UP000234907}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M6-12 {ECO:0000313|EMBL:PLS16214.1,
RC ECO:0000313|Proteomes:UP000234907};
RA Seuylemezian A., Cooper K., Vaishampayan P.;
RT "Comparitive Functional Genomics of Dry Heat Resistant strains isolated
RT from the Viking Spacecraft.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLS16214.1}.
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DR EMBL; PGVF01000016; PLS16214.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N5I2L6; -.
DR OrthoDB; 6590756at2; -.
DR Proteomes; UP000234907; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR CDD; cd05013; SIS_RpiR; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR000281; HTH_RpiR.
DR InterPro; IPR047640; RpiR-like.
DR InterPro; IPR035472; RpiR-like_SIS.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR30514; GLUCOKINASE; 1.
DR PANTHER; PTHR30514:SF19; HTH-TYPE TRANSCRIPTIONAL REGULATOR GLVR; 1.
DR Pfam; PF01418; HTH_6; 1.
DR Pfam; PF01380; SIS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51071; HTH_RPIR; 1.
DR PROSITE; PS51464; SIS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..122
FT /note="HTH rpiR-type"
FT /evidence="ECO:0000259|PROSITE:PS51071"
FT DOMAIN 163..306
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
SQ SEQUENCE 312 AA; 35040 MW; EE9089BDC3FC0126 CRC64;
MQELTWTIVQ VCFLLLQSII FQISFLVFLF YNRKNRKEVV ASMKRLLLNK ILSTVGDTIN
DTEYTILADL IDRINELQNY SIREAAKNNF VSTSSVSRLC AKLGLSGYSE LKFYLKNQYD
SLDANQDKGQ SSIKNTAYIL ADSFKEGYEK TIQQIKEADV DSFIQMLSES KQIGVCGSGI
SEIIANYFTQ RFQIIGKDAW LVNVSAPGGI YMNQLEKSQM MVVFSRSGES SYPISKALIA
KRQGVKIVAI TSNRESSLGK MSDIILPIYG SREPLDVSYS ITSYNARAVL FVDLLLQLYM
ESAPGESSGR KL
//
