ID A0A2N5I4Z9_9BACI Unreviewed; 478 AA.
AC A0A2N5I4Z9;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Sigma-54-dependent Fis family transcriptional regulator {ECO:0000313|EMBL:PLS17039.1};
GN ORFNames=CVD28_13345 {ECO:0000313|EMBL:PLS17039.1};
OS Bacillus sp. M6-12.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=2054166 {ECO:0000313|EMBL:PLS17039.1, ECO:0000313|Proteomes:UP000234907};
RN [1] {ECO:0000313|EMBL:PLS17039.1, ECO:0000313|Proteomes:UP000234907}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M6-12 {ECO:0000313|EMBL:PLS17039.1,
RC ECO:0000313|Proteomes:UP000234907};
RA Seuylemezian A., Cooper K., Vaishampayan P.;
RT "Comparitive Functional Genomics of Dry Heat Resistant strains isolated
RT from the Viking Spacecraft.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLS17039.1}.
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DR EMBL; PGVF01000011; PLS17039.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N5I4Z9; -.
DR OrthoDB; 9771372at2; -.
DR Proteomes; UP000234907; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR32071:SF120; L-LYSINE AMINOMUTASE REGULATOR; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..58
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 158..386
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 478 AA; 53179 MW; 82CF70540DF9887A CRC64;
MVPEKSLNIT NEVLEAILKS IDEGIHVIDL QGKTIFYNEV AARLDGMKIA EVLGKPLLEV
FPSLTRKTST LLQVIDRGKP IYHESQSYLN LHGEKAETMN TTLPIYVKGK LIGAVEIAKD
YSRLRMLSER LLDLESKVKR KEKPKSSNNG AIYTFDSIIT NDPVFRTVIS RGRKAGKTSS
PVLVYGESGV GKELFVQGIH NESYRRKGPF IAQNCAALPE SLLESLLFGT AKGSYTGALE
RPGLFELANG GTLFLDELNS MPVELQAKLL RVLEDGQVRR VGGAVSIPVD VRVIAAMNIM
PEQALEEKII RSDLFFRLNV LRYELPPLRN RKKDILLLTE HFISMFNTNL NLNIQGIDEQ
VSAVFVRYNW PGNVRELKHT IEYMMNVCEA DVLTAIELPG SFSGAGKKAG ADKVFPSLRK
ALRDAEVELI NKALLQTSGN ILQSAKLLGI PRQTLQYKLA KHGMEGDSHY ILDSNSKN
//
