ID A0A2N6NGH4_BEABA Unreviewed; 1746 AA.
AC A0A2N6NGH4;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Kinesin-like protein {ECO:0000313|EMBL:PMB66378.1};
GN Name=unc-104 {ECO:0000313|EMBL:PMB66378.1};
GN ORFNames=BM221_007366 {ECO:0000313|EMBL:PMB66378.1};
OS Beauveria bassiana (White muscardine disease fungus) (Tritirachium
OS shiotae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=176275 {ECO:0000313|EMBL:PMB66378.1, ECO:0000313|Proteomes:UP000235728};
RN [1] {ECO:0000313|EMBL:PMB66378.1, ECO:0000313|Proteomes:UP000235728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEF-007 {ECO:0000313|EMBL:PMB66378.1,
RC ECO:0000313|Proteomes:UP000235728};
RX PubMed=27470140; DOI=10.1007/s00253-016-7734-y;
RA Kim S., Lee S.J., Nai Y.S., Yu J.S., Lee M.R., Yang Y.T., Kim J.S.;
RT "Characterization of T-DNA insertion mutants with decreased virulence in
RT the entomopathogenic fungus Beauveria bassiana JEF-007.";
RL Appl. Microbiol. Biotechnol. 100:8889-8900(2016).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PMB66378.1}.
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DR EMBL; MRVG01000008; PMB66378.1; -; Genomic_DNA.
DR OMA; RIDKPKR; -.
DR Proteomes; UP000235728; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd22705; FHA_KIF1; 1.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF3; KINESIN FAMILY MEMBER 14-LIKE; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000235728}.
FT DOMAIN 8..358
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 1561..1725
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 619..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1423..1490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1655..1684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 751..828
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1427..1450
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1462..1490
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1655..1679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 105..112
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1746 AA; 193607 MW; 4A2B683D89DAAFAB CRC64;
MAPAGGGNIK VVVRVRPFNS REIDRGSKCI VEMKDNQTVI STPDGHGGKS AKAEAPKSFA
FDRSYWSFDK NDSNYAAQSN LFDDLGKPLL DNAFQGYNNC IFAYGQTGSG KSYSMMGYGK
EIGIIPNICQ DMFSRINQIQ ADATTKCTVE VSYLEIYNER VRDLLNPSTK GNLKVREHPS
TGPYVEDLAK LVVGSFQEIE NLMDEGNKAR TVAATNMNET SSRSHAVFTL MLTQKKYDAE
TKMEMEKVAK ISLVDLAGSE RATSTGATGA RLKEGAEINR SLSTLGRVIA ALADLSTGAK
KKKGGSQVPY RDSVLTWLLK DSLGGNSMTA MIAAISPADI NYDETLSTLR YADSAKRIKN
HAVINEDANA RMIRELKEEL ALLRSKLGGG TVGAGGAPIP ADEIYDENTP LEKQMVSITG
ADGLPKKVSK AEIAEQLSQS EKLLTDLNQT WEQKLQKTEE IHKEREAALE ELGISIEKGF
IGLHTPKKMP HLVNLSDDPL LAECLVYNLK PGTTTVGNVD TNADHQANIR LNGTRILHDH
CTFENAAADG TVTVIPSEGA SVMVNGKRIT EATQLHSGYR VILGDFHIFR FNHPMEARAE
RAEVGNSLLR QSVTASHIQA WERSTSSPTP GSRPGHERAY SKASDFGDLS RPESPSLRNN
RDTDWSAARR EAAGAILGSD QTNFTSLTDE ELNALFEEVQ RARAERVIVR EDGEDTESVT
SYQLREKYMS NGTIDNFSLD TALTMPSTPK QGEAEDRLRE VREELQSQLE KQKEEFQDQL
KSAEAANVEV EEIKREKVKM EAALQELKED MQKQLKMQKK QFEDKIEKMD PLKRPKASSK
LSEGELERAK KVIGIWRDRH YVKMAETVLQ NAAVLKEAQI MSNELDESVV FQFAVVDVGH
VMCSSYDMVL NGLTSEGEDV ALEETPKPCI GIRVIDYRNN VVRLWSLEKL HDRVRQMRQM
HQYLDQPEYA QHLSLDNPFI EHCMPSYTLI GEVDVPLKAV FESRVQDFSL DVLSPYTSHA
IGIVKLSLEP SHARAPTNTL KFNVVMHEFI GFAEREGTEV HAQLFIPGVS EEDGVTTTQM
ITEFDEGPIR FESVHNMSVP LFAPQDVMLR ASIYAKVQPM HLDKLLSWDD MRDAAPSRDG
TKASRINEAQ FYTQEKHDML SRIQILELNE MGEYAPVEVT QVSELDTGTF QLHQGLQRRI
AINIAHSSGD ALPWGDVTAV RVGKVRLVDS GGKTPDMGAS EPDIQLRLTS HPIFRQNPNG
TRSITVFAQW DSSLHNSLLL DRVTADKYKV QMSISWEISS EKLAEPMKFS QKVCIQVLSR
TFVRQTSMFS ALWQNMRFIR SSTGIFTITM RPAPIKRVGD LWRMNSRHDY VKGEENLDSW
NPRGVSLVSD FILARKKRRR IAEIGAVHMM LHVLGIDPSG QLVKEASEPE PEPEIQKPVL
PDDDDLLHDT PEASQVPCLE EEAEARAADA GIEDEAKGEG EADGEETVKV EVSATSEKPI
YNEQQVELLQ QCLSLWLKYP DPLAKILSPA NTAPPTNGVT SEPPELPSLI TTVVRVSKNP
KVLKGGYLLV PNSDSTRWVK RFVELRRPYL HIHSASDGDE VALVSLRNSR VDSQPGVLAL
LNGPDDYDNA PGQNGGADFI PGHRRTASGR VISTIWTGNN NGGSSSSSSS GTRANNGGGP
GLQRLSERMQ AGVFAIYGTD NTWLFAARSE RDKMDWIFRI DQTYMSAAGE SQPGSGFASP
HPGSDY
//
