ID A0A2N6NJX0_BEABA Unreviewed; 171 AA.
AC A0A2N6NJX0;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=NADH-ubiquinone oxidoreductase {ECO:0000256|PIRNR:PIRNR017016};
GN Name=B1O14.280 {ECO:0000313|EMBL:PMB67526.1};
GN ORFNames=BB8028_0006g07190 {ECO:0000313|EMBL:PQK16399.1}, BM221_007195
GN {ECO:0000313|EMBL:PMB67526.1};
OS Beauveria bassiana (White muscardine disease fungus) (Tritirachium
OS shiotae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=176275 {ECO:0000313|EMBL:PMB67526.1, ECO:0000313|Proteomes:UP000235728};
RN [1] {ECO:0000313|EMBL:PMB67526.1, ECO:0000313|Proteomes:UP000235728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEF-007 {ECO:0000313|EMBL:PMB67526.1,
RC ECO:0000313|Proteomes:UP000235728};
RX PubMed=27470140; DOI=10.1007/s00253-016-7734-y;
RA Kim S., Lee S.J., Nai Y.S., Yu J.S., Lee M.R., Yang Y.T., Kim J.S.;
RT "Characterization of T-DNA insertion mutants with decreased virulence in
RT the entomopathogenic fungus Beauveria bassiana JEF-007.";
RL Appl. Microbiol. Biotechnol. 100:8889-8900(2016).
RN [2] {ECO:0000313|EMBL:PQK16399.1, ECO:0000313|Proteomes:UP000237441}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 8028 {ECO:0000313|EMBL:PQK16399.1,
RC ECO:0000313|Proteomes:UP000237441};
RA Valero Jimenez C.A., Zwaan B.J., Van Kan J.A., Takken W., Debets A.J.,
RA Schoustra S.E., Koenraadt C.J.;
RT "Comparative genomics of the entomopathogenic fungus Beauveria bassiana.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000256|PIRNR:PIRNR017016}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|PIRNR:PIRNR017016}.
CC -!- SIMILARITY: Belongs to the complex I NDUFA8 subunit family.
CC {ECO:0000256|ARBA:ARBA00010705, ECO:0000256|PIRNR:PIRNR017016}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PMB67526.1}.
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DR EMBL; MRVG01000007; PMB67526.1; -; Genomic_DNA.
DR EMBL; JRHA01000006; PQK16399.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N6NJX0; -.
DR EnsemblFungi; BB8028_0006g07190.1; BB8028_0006g07190.1; BB8028_0006g07190.
DR OMA; RQVNQCA; -.
DR OrthoDB; 1327569at2759; -.
DR Proteomes; UP000235728; Unassembled WGS sequence.
DR Proteomes; UP000237441; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro.
DR InterPro; IPR010625; CHCH.
DR InterPro; IPR016680; NDUFA8.
DR PANTHER; PTHR13344:SF0; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8; 1.
DR PANTHER; PTHR13344; NADH-UBIQUINONE OXIDOREDUCTASE; 1.
DR Pfam; PF06747; CHCH; 1.
DR PIRSF; PIRSF017016; NDUA8; 1.
DR PROSITE; PS51808; CHCH; 2.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Electron transport {ECO:0000256|ARBA:ARBA00022982,
KW ECO:0000256|PIRNR:PIRNR017016}; Membrane {ECO:0000256|PIRNR:PIRNR017016};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW ECO:0000256|PIRNR:PIRNR017016};
KW Mitochondrion inner membrane {ECO:0000256|PIRNR:PIRNR017016};
KW Reference proteome {ECO:0000313|Proteomes:UP000235728};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Respiratory chain {ECO:0000256|ARBA:ARBA00022660,
KW ECO:0000256|PIRNR:PIRNR017016};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR017016};
KW Ubiquinone {ECO:0000313|EMBL:PMB67526.1}.
FT DOMAIN 91..124
FT /note="CHCH"
FT /evidence="ECO:0000259|Pfam:PF06747"
SQ SEQUENCE 171 AA; 19530 MW; B2CFDE92C9583667 CRC64;
MSTRRPQFNQ QVLIDATPLP DDIPAVKEIG ASSAPLLSAS FFIGARCRDY NDDYMQCKTE
NPGRGEFDCM KEGRRVTRCA QSVIKDINTH CLAEFRKHWE CLDDRNHQLW QCRPAEWKLN
KCVFDNLKLE KKIPDQPPNV VPVELRPKQI FADFPIGPGE GKPFVAGQSK Q
//
