ID A0A2N6NLN7_BEABA Unreviewed; 834 AA.
AC A0A2N6NLN7;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Transmembrane E3 ubiquitin-protein ligase 1 {ECO:0000313|EMBL:PMB68188.1};
GN Name=TUL1 {ECO:0000313|EMBL:PMB68188.1};
GN ORFNames=BM221_006365 {ECO:0000313|EMBL:PMB68188.1};
OS Beauveria bassiana (White muscardine disease fungus) (Tritirachium
OS shiotae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=176275 {ECO:0000313|EMBL:PMB68188.1, ECO:0000313|Proteomes:UP000235728};
RN [1] {ECO:0000313|EMBL:PMB68188.1, ECO:0000313|Proteomes:UP000235728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEF-007 {ECO:0000313|EMBL:PMB68188.1,
RC ECO:0000313|Proteomes:UP000235728};
RX PubMed=27470140; DOI=10.1007/s00253-016-7734-y;
RA Kim S., Lee S.J., Nai Y.S., Yu J.S., Lee M.R., Yang Y.T., Kim J.S.;
RT "Characterization of T-DNA insertion mutants with decreased virulence in
RT the entomopathogenic fungus Beauveria bassiana JEF-007.";
RL Appl. Microbiol. Biotechnol. 100:8889-8900(2016).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PMB68188.1}.
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DR EMBL; MRVG01000006; PMB68188.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N6NLN7; -.
DR OMA; LEGWMRF; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000235728; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:UniProt.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR024766; Znf_RING_H2.
DR PANTHER; PTHR22763; RING ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR22763:SF165; TRANSMEMBRANE E3 UBIQUITIN-PROTEIN LIGASE 1; 1.
DR Pfam; PF12678; zf-rbx1; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000235728};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:PMB68188.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..834
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014749872"
FT TRANSMEM 407..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 585..606
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 612..630
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 642..663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 769..828
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 503..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 834 AA; 90926 MW; C522F5052590EC0D CRC64;
MPPRQQTGVS FAFVILMIWL LMPMGDIVGQ TGPLLSAIAA RRLARYRDAL AVLNGTHWGD
FAPTAQDAPA FLNMTGFREI DGFAWEDLDR FREKSVQLSR HAVASAPDKP PLWDTAEGEP
VWTTASGSLE GQWVYSPGSV PRSYDSYNLS NSVPDMDWIG DHISWGRNLT GSAGLMHLHL
ESNTTTTAFE QLPRDQAPLA GGSIRHVKGT LSLEDTMGSQ STWDMRLWGV HWPRQGVVLM
TTTSEKYEGI FGLPHLTPGP DYFQSSKALL TQRLGKVLDA KERNVYSDQT VPWSAETQSS
PQFLLSPAPQ CEMILYAQVH PPDRDRLRGG AAAKDTLEMA QLIAAIEDEL ATPRGAPVGT
VPPLRMSVVV YSPDCGFFLE SKGPPAFPPS EANHLAGVKA EVQTHRIKTW LLIFACVVFG
QVFLLKNQMK ETFTPSTMGR VSFGTVASMV MVDGITFTAS ATWVSSAGAT FLPTMALMFA
AFLSMTIGGS FLAKIYEVQF PENNPRPEPS TNTTPSPAAL PSASLLPGPV TAPGGLPPRQ
SPVIVPLDGD VDADFTSGAA ALPSRATLAA APSTNTSPRQ NFQAIIGRFV LISLVLGFVT
LSSSTWYPSA RATYLDICAF AYLSLWTPQI RRNAVRNCRR ALAWSFVLGQ SLLRITPIAY
FWLNPDNFLF ARTSPRAFAA LAAWLWLQLV VLAAQDVLGP RFAVPARWLP DAWDYHPVLR
ADNVEAGGLP IGLLAVDEAM EPAHDGGARR RSSSAATGEK ATARHVIDCS ICQEILEVPV
VRVGDDDGGG VASVFARRMY MVTPCRHIFH TACLESWMKF RLQCPICRED LPPL
//
