ID A0A2N6NRH5_BEABA Unreviewed; 807 AA.
AC A0A2N6NRH5;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Homeobox protein HD-12 {ECO:0000313|EMBL:PMB69856.1};
GN Name=HD-12 {ECO:0000313|EMBL:PMB69856.1};
GN ORFNames=BM221_004503 {ECO:0000313|EMBL:PMB69856.1};
OS Beauveria bassiana (White muscardine disease fungus) (Tritirachium
OS shiotae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=176275 {ECO:0000313|EMBL:PMB69856.1, ECO:0000313|Proteomes:UP000235728};
RN [1] {ECO:0000313|EMBL:PMB69856.1, ECO:0000313|Proteomes:UP000235728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEF-007 {ECO:0000313|EMBL:PMB69856.1,
RC ECO:0000313|Proteomes:UP000235728};
RX PubMed=27470140; DOI=10.1007/s00253-016-7734-y;
RA Kim S., Lee S.J., Nai Y.S., Yu J.S., Lee M.R., Yang Y.T., Kim J.S.;
RT "Characterization of T-DNA insertion mutants with decreased virulence in
RT the entomopathogenic fungus Beauveria bassiana JEF-007.";
RL Appl. Microbiol. Biotechnol. 100:8889-8900(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PMB69856.1}.
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DR EMBL; MRVG01000004; PMB69856.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N6NRH5; -.
DR OMA; CAFESEL; -.
DR Proteomes; UP000235728; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR11850:SF102; HOMEOBOX PROTEIN HOMOTHORAX; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000235728}.
FT DOMAIN 90..153
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 92..154
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 46..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 217..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 689..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 807 AA; 90285 MW; E04CE76DFEC0615F CRC64;
MDSFDLALPG FGHDVSAIDN DSLQYDIFQD WDVLNEFTLL GQQLGEQHTP AEEAPVDPVP
IQNNDTPETT PMSQTASTPY FPSPPVTTPS DTAGARPGFP QSAVRLLRQW MTANSHYPYP
TREDKEMLST MTGLSQTQII NWFANARRRA KMSAPLRAPA STTESMAPMD IPARRATPGI
LEGLNPMQRW ENSPPDNEPA DVAAILGAVN AARIAASPSD RSCLTPASRY SDDSSSVGFS
NGSSFGRYDA PSSEGSVRSA RSSQGGVSLS PFPDSSARRR RRRKRAGLPT HTAYPTPIRG
AFQCTFCAED FQTKYDWQRH EKTWHLSIDR WVCAPTGPLS VDPVTGSLTC VFCMQPNPDA
AHFESHNFSL CSSRTLTERT FYRKDHLTQH LRLGHHAKVP KETLETWKAA SPEIRSRCGF
CNTTLHSWSA RVDHLALHFK NGASMEHWTG DWGFTEAVLR TVENSVPPYL IHLEKISPLP
YLASSASPWT PNSPYELLNM ELEYWIANHT DDTGSPPTDT EIQLEACRII RSADILSTDP
TAACGSWLRD LVMSCKEITR DAMFQSVRGQ EENRMSTLRI NGKDNIFQDC AFESELRQFT
LSLPQNGKEV ANWELQVEAD RVLRRAQQLS NSNKDNVLNW LLRLTYNSTD WLVDFRRRLF
EAMEQGEKVS EISPPAGDAT TLDPEALGVE SPMSLDSTQQ DPTKERHKAA TASRRGFYDL
NDANGYRRLA RGLARFVASS MSDCNPNKHI PSDEEIQQQA RWLEYGEGDP WNQTAADLPD
WLERFKRDIG LLPRDTGPGL GLINRKT
//
