ID A0A2N6NWF2_BEABA Unreviewed; 455 AA.
AC A0A2N6NWF2;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Tryptophan 2-halogenase {ECO:0000313|EMBL:PMB71592.1};
GN Name=cmdE {ECO:0000313|EMBL:PMB71592.1};
GN ORFNames=BM221_001682 {ECO:0000313|EMBL:PMB71592.1};
OS Beauveria bassiana (White muscardine disease fungus) (Tritirachium
OS shiotae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=176275 {ECO:0000313|EMBL:PMB71592.1, ECO:0000313|Proteomes:UP000235728};
RN [1] {ECO:0000313|EMBL:PMB71592.1, ECO:0000313|Proteomes:UP000235728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEF-007 {ECO:0000313|EMBL:PMB71592.1,
RC ECO:0000313|Proteomes:UP000235728};
RX PubMed=27470140; DOI=10.1007/s00253-016-7734-y;
RA Kim S., Lee S.J., Nai Y.S., Yu J.S., Lee M.R., Yang Y.T., Kim J.S.;
RT "Characterization of T-DNA insertion mutants with decreased virulence in
RT the entomopathogenic fungus Beauveria bassiana JEF-007.";
RL Appl. Microbiol. Biotechnol. 100:8889-8900(2016).
CC -!- SIMILARITY: Belongs to the flavin-dependent halogenase family.
CC {ECO:0000256|ARBA:ARBA00005706}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PMB71592.1}.
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DR EMBL; MRVG01000002; PMB71592.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N6NWF2; -.
DR OMA; ESAIWAR; -.
DR Proteomes; UP000235728; Unassembled WGS sequence.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006905; Flavin_halogenase.
DR PANTHER; PTHR43747:SF1; FAD-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43747; FAD-BINDING PROTEIN; 1.
DR Pfam; PF04820; Trp_halogenase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000235728}.
SQ SEQUENCE 455 AA; 50052 MW; 242CF0C91EBC76BE CRC64;
MFESTEVKQI LFARERENTA AVPDDDEVTV DAPRPESAIW ARKNGTSGSI SFKYLVDASG
RQGILSTKYL KNRRVNDNFK NVANWAYWKS DNIYGPGTHM QGSPYFEALD DASGWAWFMP
LHDGTRSVGI VQDQKQAARA KRDLGRPSGL EYYKLALKMA PTTQNLLAGA ELASDVRSAS
DWSYTASTYH LPNARICGDA GSFIDPLFSS GVHLAITGGL SAAATIAASV RGDCDENTAG
AWHSKKTVQS YSRFFLAVSS ATKQIREKHL PILQDLNEEG FQRAFDLFRP IIQGTVDNDT
RSKVTQAEIL KILEFCSKSF TYVAPEQKEA LFKKLTKLGV NGEDSDVSWA NGLGDLQHHL
TADELKVLGI LQSRRLTRED PFEIDSFTLD PIDGLAPSLV RGSLGLVKSE QARIDPGCLF
SPEFLDGKMP GIREGSIFHS SDEDRLNKGA VETVA
//
