ID A0A2N6SL83_9LACT Unreviewed; 649 AA.
AC A0A2N6SL83;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=PTS fructose transporter subunit IIC {ECO:0000313|EMBL:PMC57810.1};
GN ORFNames=CJ205_07690 {ECO:0000313|EMBL:PMC57810.1};
OS Dolosicoccus paucivorans.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Dolosicoccus.
OX NCBI_TaxID=84521 {ECO:0000313|EMBL:PMC57810.1, ECO:0000313|Proteomes:UP000235682};
RN [1] {ECO:0000313|EMBL:PMC57810.1, ECO:0000313|Proteomes:UP000235682}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UMB0852 {ECO:0000313|EMBL:PMC57810.1,
RC ECO:0000313|Proteomes:UP000235682};
RA Thomas-White K., Kumar N., Forster S., Putonti C., Lawley T., Wolfe A.J.;
RT "Bacterial strain isolated from the female urinary microbiota.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PMC57810.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PNHE01000044; PMC57810.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N6SL83; -.
DR STRING; 84521.SAMN04487994_10306; -.
DR OrthoDB; 9782569at2; -.
DR Proteomes; UP000235682; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005351; F:carbohydrate:proton symporter activity; IEA:InterPro.
DR GO; GO:0022877; F:protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR CDD; cd00211; PTS_IIA_fru; 1.
DR CDD; cd05569; PTS_IIB_fructose; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR InterPro; IPR036095; PTS_EIIB-like_sf.
DR InterPro; IPR013011; PTS_EIIB_2.
DR InterPro; IPR003501; PTS_EIIB_2/3.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013014; PTS_EIIC_2.
DR InterPro; IPR004715; PTS_IIA_fruc.
DR InterPro; IPR003353; PTS_IIB_fruc.
DR InterPro; IPR006327; PTS_IIC_fruc.
DR NCBIfam; TIGR00829; FRU; 1.
DR NCBIfam; TIGR00848; fruA; 1.
DR NCBIfam; TIGR01427; PTS_IIC_fructo; 1.
DR PANTHER; PTHR30505; FRUCTOSE-LIKE PERMEASE; 1.
DR PANTHER; PTHR30505:SF28; PTS SYSTEM 2-O-ALPHA-MANNOSYL-D-GLYCERATE-SPECIFIC EIIABC COMPONENT; 1.
DR Pfam; PF00359; PTS_EIIA_2; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR Pfam; PF02302; PTS_IIB; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
DR PROSITE; PS00372; PTS_EIIA_TYPE_2_HIS; 1.
DR PROSITE; PS51099; PTS_EIIB_TYPE_2; 1.
DR PROSITE; PS51104; PTS_EIIC_TYPE_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000235682};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 306..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 524..545
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..577
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 625..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..149
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|PROSITE:PS51094"
FT DOMAIN 175..270
FT /note="PTS EIIB type-2"
FT /evidence="ECO:0000259|PROSITE:PS51099"
FT DOMAIN 298..649
FT /note="PTS EIIC type-2"
FT /evidence="ECO:0000259|PROSITE:PS51104"
SQ SEQUENCE 649 AA; 68596 MW; 90DA34DCE4D5A550 CRC64;
MQLTQLLLKE AMDLDLQAST RDEAIRQLAE TFHEVGGVSD AEAYIEALMA REAQSTTGVG
DHIAIPHAQH ESITQPAIIF ARSKQGIDWS SFDGQDVNYI FMIAAPKGGG GEHLDALAKL
SQVLMNPEVH EALATVSTPE EVVDIFAKFE KPEEEEAVVE EVVEEPAVSS DRPYILAVTA
CPTGIAHTFM AEEKLKQTAA ELGYDIKVET NGQSGIGNRL TKQDIDRAVG IIVAADKQVE
MARFNGKPVL ITKVADGINK PQELLDRAAT GDLPIYHSTY EGGEDFEDAE EESLGRKFYK
HLMNGVSHML PFVVAGGILI ALSFFWGINA ADPTSPEYNP IAQTLNLLGG LSFAMMLPVL
SGYIGQSLAD RPGLVIGMMG GVFANPDILS AFGGGQGLFE NSVSSGFLGA LVAGFLAGGI
VWFLKKAFSW LPKALEGMKP IFLYPLFGVL LMGLIMLFVV NGPMGAVMNG IMNFINSIPQ
EYSILLGFLV AAMMAVDMGG PINKAAYVTG TALVTASGNA GSNVMAAVMI GGMVPPLAIA
LSATFNKNLW PAAQRNSALV NYVMGAAFIT EGAIPFAAVN PLRVIPSVAI GSGVAGALSI
FFGSVSKVPH GGIFAVLAGG VSNPFMYLVA WIIGGIVGAV LLNVLLKEK
//
