ID A0A2N6V0S9_9ACTO Unreviewed; 1484 AA.
AC A0A2N6V0S9;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=FtsK domain-containing protein {ECO:0000259|PROSITE:PS50901};
GN ORFNames=CJ184_01570 {ECO:0000313|EMBL:PMC90874.1};
OS Actinotignum urinale.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinotignum.
OX NCBI_TaxID=190146 {ECO:0000313|EMBL:PMC90874.1};
RN [1] {ECO:0000313|EMBL:PMC90874.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UMB0759 {ECO:0000313|EMBL:PMC90874.1};
RA Thomas-White K., Kumar N., Forster S., Putonti C., Lawley T., Wolfe A.J.;
RT "Bacterial strain isolated from the female urinary microbiota.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PMC90874.1}.
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DR EMBL; PNHX01000001; PMC90874.1; -; Genomic_DNA.
DR STRING; 1120933.GCA_000420445_00729; -.
DR OrthoDB; 9807790at2; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 2.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50901; FTSK; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 533..734
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 924..1143
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 556..563
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 944..951
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1484 AA; 164931 MW; 7487309B5DD2997E CRC64;
MDAIKKRDNA VKTVPKNSVL LQLFAPTIES VALPPEVPKK NTRTRLLTAC MPLIGSLGII
VFMIFSPAKN PLMILTAGLM GIGCLAVSVG TISASSKERR REIMLLREKY ATYLDHCRDK
IRNSLRGNRV EALKKYPDPH ILPFKVESDK VWRKCNVDEV RIGRASQKGM YEASVATELS
ETSPDQFLPH NSTPQKLSSP HAPTFQLPAE YDHVSEKWRS RLIDTYANQN NMPAVIDFSA
RNVWIIRGKS EVVQAWLRAI LCNIAMWVNP NYVKIVLKIH TGKYEWLRWL PHLDSVASKR
LLICEGYVPE NLKNGDIALC VNIKNEKEMY ERYSPVRVVD ISHKKVNRPG SIFSRVAQNI
QGIKRMWRIR DTARVGCDSA RVGCDSARVA RDRTLVTRDT AQATQETQPF YETHGIREPV
QPDYSPTNGG ITELHVLEIK GENNGNNLNV EPLFTCLADM LQYAEAETIA RGLARKWIHM
PDLSNSDAVE KNRVNLQESG SLLHITGADI SQAKNRFPAD KYLCVPVGVK KDGAPLWLNL
NESARGGSGP HGLIIGATGS GKSELLKNIL FCLAATHDSR QLNYLLVDFK GGATFQDLEK
LPHTAAVVTN LAGDIGLVAR METAIRSEIE RRQETLARAG GYANIHTYMQ AKDRGEHDFP
DLAELLIVVD EFSELLATSP EFHAVFMALG RVGRSLGMHL ILASQRIEDS AMRGLDTHMS
FRIALRTFST YESRSVIGED SAFYLPQQPG AAYLSCGAES PEFFQAYYIS EPMKIPQDLE
IYPSGAGETR VLQAEQPKLQ NYKKATEKER LCTEDKEMVW SGLRGSNFTL KDRLEDIRRR
KTSPIPSTSS VTTLDLPTEI IRATQGQQPA HCMWLPPLET SPSVDNLWEE WRNKSNPVSE
ERLGAQGEIG DIFPVAYCDL PQLQQRTILT LEATGRKGHI AVVGGQQSGK TNALATIMCS
VGRALSPHNA NFYVIDIAGG GLKPWAELPH VATYASRKET EKIQHITAHL LQVMEERESS
GQELHVSVSR DERLLDYESG GQEFPCQETQ NPDSYNHHNP TSQAFCTPLH GNVPLFVFVD
GWGYLRNDFP DIEEQLTSLL ERGGAQNIYV VATAMRWSQF RMATAELFGT IVELQLGDAF
DSRISRTESQ RIPSTPGRGL IEGGHHILWA LPDKNSVRVE EIWNGVRAKK LQTLPEFVGY
ERGYLELAST GVPKDNGKLA GNETSSINSH VKGDDILHIG NHVIGGESAH ISNTIASYEA
SNRRNNVTGC DTVKARMIPP MFFGETVGGK KVMFDFNMAT ALLIHGPRRT GKTSMLRLLC
TEICRIHEPG EAKIFAFDAG DSFANNILPD YLGAHIRTVQ EMRQIIAELA DYCEKRIAGQ
RKITTHAYVI IDDYDVLLAS TSATFGSEPL LPLLPLLATA EKIGLHIILA SANNATGFTS
DSVTRFLNMR ESPKIIFDDA GGTPGKARLI HGNTRTEVQI AYVS
//
