ID   A0A2N7DBK4_9VIBR        Unreviewed;       255 AA.
AC   A0A2N7DBK4;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=Pyruvate dehydrogenase complex repressor {ECO:0000256|ARBA:ARBA00039592};
GN   ORFNames=BCU68_06170 {ECO:0000313|EMBL:PMH41263.1};
OS   Vibrio sp. 10N.286.49.B3.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=1880855 {ECO:0000313|EMBL:PMH41263.1, ECO:0000313|Proteomes:UP000235563};
RN   [1] {ECO:0000313|Proteomes:UP000235563}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=10N.286.49.B3 {ECO:0000313|Proteomes:UP000235563};
RA   Kauffman K., Hussain F., Yang J., Arevalo P., Brown J., Cutler M.,
RA   Kelly L., Polz M.F.;
RT   "Nontailed viruses are major unrecognized killers of bacteria in the
RT   ocean.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcriptional repressor for the pyruvate dehydrogenase
CC       complex genes aceEF and lpd. {ECO:0000256|ARBA:ARBA00037357}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PMH41263.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MCUV01000035; PMH41263.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N7DBK4; -.
DR   OrthoDB; 5450856at2; -.
DR   Proteomes; UP000235563; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011711; GntR_C.
DR   InterPro; IPR008920; TF_FadR/GntR_C.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43537:SF34; PYRUVATE DEHYDROGENASE COMPLEX REPRESSOR; 1.
DR   PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR   Pfam; PF07729; FCD; 1.
DR   Pfam; PF00392; GntR; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00895; FCD; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000235563};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          9..77
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50949"
SQ   SEQUENCE   255 AA;  28908 MW;  987F62DABFD3FB8E CRC64;
     MTYQRIRQPK LSDVIEQELE RLIVEGTLAP GQQLPPEREL AKQFDVSRPS IREAIQRLEA
     KHLLTRRQGG GTFVSTDVWK SFSDPLLDLL SSHPETQLDL LESRHAMEGI SAYFAALRGT
     DEDFARIKAC QEAIHQSQQD NDVKAEASAV MGFLVALTEA AHNVVLLHIV RSLAPLLEQN
     MLQNLKLLHR RTEVVNSVSK HRANIVDAII SGQPEKAREM SHSHLAYIEE TLLDLTKEQS
     RRERSLRRIE QGKES
//