ID A0A2N7TM47_9GAMM Unreviewed; 538 AA.
AC A0A2N7TM47;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=C1H66_11840 {ECO:0000313|EMBL:PMR69263.1};
OS Halomonas heilongjiangensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1387883 {ECO:0000313|EMBL:PMR69263.1, ECO:0000313|Proteomes:UP000235346};
RN [1] {ECO:0000313|EMBL:PMR69263.1, ECO:0000313|Proteomes:UP000235346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26881 {ECO:0000313|EMBL:PMR69263.1,
RC ECO:0000313|Proteomes:UP000235346};
RA Chen C.;
RT "Halomonas endophytica sp. nov., isolated from storage liquid in the stems
RT of Populus euphratica.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PMR69263.1}.
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DR EMBL; PNRE01000051; PMR69263.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N7TM47; -.
DR OrthoDB; 9804645at2; -.
DR Proteomes; UP000235346; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR44936; SENSOR PROTEIN CREC; 1.
DR PANTHER; PTHR44936:SF10; SENSOR PROTEIN RSTB; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:PMR69263.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000235346};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 238..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 259..311
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 319..534
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 538 AA; 60173 MW; 04DFED4E30318C6A CRC64;
MRRALADSTF LRVYVLLALA LLLTFGLALL GLAMVDQVRR EHHREQLADA PMRLLVEKLA
ELPRDEREAW LERRAERLDM TPTLYPVDSL VLNYFDRTRL ESGRVLVSFR GEHGWRLQRL
LPGGDWLLEI DLAGLSEQQL RGLTELFGEW LSEVQGAERQ QRLEWVSGAG IPVTLTDRAP
EGLDARQLSR LAEGEVVIRL LPGRWSITMY LELPDTDGEA RWLAIGPVQA FEPMPGSLQL
LLLMILLGVL AVIIYLIVRG VEARMARLEL AATRIAGGRL DTRVKVESGD FLGRLGMAFN
GMATQVQSLL RAQQDMIRAV SHELRTPVAR IRFAVQMVED MTDDPAIRRQ LEGIDGDIEE
LDGLIDEILT YARLGNESVN SMEMDTSLVD CRAMAERVIE TLSPLHGHLR FELAGGDEVE
ISADPRYLQR ALQNLVANAC RHARSRVLIR LHSEPHLVRL DVEDDGPGVP VSERLEVFKP
FARLDDSRTR SSGGYGLGLS IVQKVMTWHG GSVAVDDSPQ LGGARFTLLL PRRPVTPA
//
