ID A0A2N7UMF9_9GAMM Unreviewed; 402 AA.
AC A0A2N7UMF9;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:PMR81633.1};
GN ORFNames=C1H70_04350 {ECO:0000313|EMBL:PMR81633.1};
OS Halomonas urumqiensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1684789 {ECO:0000313|EMBL:PMR81633.1, ECO:0000313|Proteomes:UP000235547};
RN [1] {ECO:0000313|EMBL:PMR81633.1, ECO:0000313|Proteomes:UP000235547}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BZ-SZ-XJ27 {ECO:0000313|EMBL:PMR81633.1,
RC ECO:0000313|Proteomes:UP000235547};
RA Chen C.;
RT "Halomonas endophytica sp. nov., isolated from storage liquid in the stems
RT of Populus euphratica.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PMR81633.1}.
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DR EMBL; PNRG01000008; PMR81633.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N7UMF9; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000235547; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000235547};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:PMR81633.1}.
FT DOMAIN 6..229
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 281..401
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 92
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 358
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 388
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 402 AA; 42337 MW; 1D17AC2F5E3D4175 CRC64;
MSNQAFIYEA VRTPRSKGKI DGTLHEVKPV DLGAGLLRGL QQRLDLDTAY VDDVVFGCVT
PVSEQGSDVT KMIVQNAEWD QSVAGVQLDR FCASGLEAVN TAAQKVASGW DQLVVAGGIE
CMSRVPMGSN GGAMGGDPGF SMKTGFVPQG IGADLIATID GYSREDVDAF ALQSQLRAAN
ARDNGYFDRS VLPVLDRNGL LILERDDFIK PATTLQGLAA LKPSFTTMGQ FGFDDVALRH
YPEVERIEHV HTPGNSSGIV DGASAVLIGT EQAGRDLGLA PRGRVVATAV LATDPVIMLA
GPGPAALKCL KTAGLTPDDI YLWEINEAFA SVALRYMKDL GIDASVTNVN GGSIAMGHPL
GATGGMLVSI MLDELERRGL KRGMLSLCVG GGMGISTIIE RV
//
