ID   A0A2N8N722_9BACT        Unreviewed;       443 AA.
AC   A0A2N8N722;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   RecName: Full=Multidrug-efflux transporter {ECO:0000256|ARBA:ARBA00031636};
GN   ORFNames=BHU16_06265 {ECO:0000313|EMBL:PNE24579.1};
OS   Tannerella sp. oral taxon 808.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC   Tannerella.
OX   NCBI_TaxID=712711 {ECO:0000313|EMBL:PNE24579.1, ECO:0000313|Proteomes:UP000235918};
RN   [1] {ECO:0000313|EMBL:PNE24579.1, ECO:0000313|Proteomes:UP000235918}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Cell103 {ECO:0000313|EMBL:PNE24579.1};
RA   Beall C.J., Campbell A.G., Griffen A.L., Podar M., Leys E.J.;
RT   "Genomics of the uncultivated, periodontitis-associated bacterium
RT   Tannerella sp. BU045 (oral taxon 808).";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PNE24579.1}.
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DR   EMBL; MIQB01000046; PNE24579.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N8N722; -.
DR   Proteomes; UP000235918; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR   CDD; cd13138; MATE_yoeA_like; 1.
DR   InterPro; IPR002528; MATE_fam.
DR   InterPro; IPR048279; MdtK-like.
DR   NCBIfam; TIGR00797; matE; 1.
DR   PANTHER; PTHR43298:SF2; FMN_FAD EXPORTER YEEO-RELATED; 1.
DR   PANTHER; PTHR43298; MULTIDRUG RESISTANCE PROTEIN NORM-RELATED; 1.
DR   Pfam; PF01554; MatE; 2.
DR   PIRSF; PIRSF006603; DinF; 1.
PE   4: Predicted;
KW   Antiport {ECO:0000256|ARBA:ARBA00022449};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000235918};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        9..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        47..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        95..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        134..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        167..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        192..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        231..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        280..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        314..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        354..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        381..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        411..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   443 AA;  47733 MW;  64994999661BD652 CRC64;
     MSQDLTRGAV WRVIPAFALP LLVGNLTQQV YNLTDSVIVG RFLGKEALAA VSASFFIYYF
     IISLAIGVGS GITVVVSQRF GARDHEAVQR AFSSFLLFAL VAGAVLSVVG VVGADGFFRL
     TQTPPEVMPY ALRYFRVYAA GTLFFILFYS ALSILRGIGD SVRPMHFVLT TAVLNIAFDL
     LFILVFRWDI EGAAAATVLA QACGVALAVR HIRRHELLSL RRRDLAFDRP LFLLGVRIGI
     PTGVQQCAIA IGLVALLGIV NGFGADTLTA YGAAGKIDSF IVQIILTLSG ALSAFCGQNI
     GAGRLDRVHA GVRFAMLFNV CLCLVVLAAI LAFGRQMMGA FTEDADVMAI GQEYLTILGA
     VLVFHGALCI LNGAMRGAGD TLFAMTTGIV SFWLIRIPLA TLFSRTWGRV GIWWAIAASI
     TLAFVATLIY YRTGRWKRRA GLG
//