ID   A0A2N9JFN9_9ACTN        Unreviewed;       229 AA.
AC   A0A2N9JFN9;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Sodium/hydrogen exchanger family protein {ECO:0000313|EMBL:SPD86573.1};
GN   ORFNames=MPLG2_1537 {ECO:0000313|EMBL:SPD86573.1};
OS   Micropruina glycogenica.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Micropruina.
OX   NCBI_TaxID=75385 {ECO:0000313|EMBL:SPD86573.1, ECO:0000313|Proteomes:UP000238164};
RN   [1] {ECO:0000313|EMBL:SPD86573.1, ECO:0000313|Proteomes:UP000238164}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1 {ECO:0000313|EMBL:SPD86573.1};
RA   Cohen D.B., Kent A.D.;
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; LT985188; SPD86573.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2N9JFN9; -.
DR   KEGG; mgg:MPLG2_1537; -.
DR   Proteomes; UP000238164; Chromosome 1.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR   GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR   PANTHER; PTHR32507:SF0; NA(+)_H(+) ANTIPORTER 2-RELATED; 1.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000238164};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        51..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        93..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          3..179
FT                   /note="Cation/H+ exchanger"
FT                   /evidence="ECO:0000259|Pfam:PF00999"
SQ   SEQUENCE   229 AA;  23944 MW;  1065FBF8AA9DA2DE CRC64;
     MFASAIVGRK DVPARLRRLL SVESGLNDGI ALPVVLLLIS AAGTTQEHSD LGLVALELVG
     GLALGVLLPL AVHQLLRIPG LGAEPRLQPL RPVAIAIMLY GIAHLTGANP YLAAFAGGFM
     TARLSPKAQE AFEQLGEMLA ELAKFAALLV FGALLRPQLF VSIGFGGWMV ATLALVLVRP
     ASLAASLGGR RPDSSGVVRR SLVRPEGFRL CGVRAAGAAL GHTQRRRGL
//