ID A0A2N9JKZ3_9ACTN Unreviewed; 624 AA.
AC A0A2N9JKZ3;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=ABC-type multidrug transport system ATPase and permease component {ECO:0000313|EMBL:SPD88446.1};
GN ORFNames=MPLG2_3416 {ECO:0000313|EMBL:SPD88446.1};
OS Micropruina glycogenica.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Micropruina.
OX NCBI_TaxID=75385 {ECO:0000313|EMBL:SPD88446.1, ECO:0000313|Proteomes:UP000238164};
RN [1] {ECO:0000313|EMBL:SPD88446.1, ECO:0000313|Proteomes:UP000238164}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1 {ECO:0000313|EMBL:SPD88446.1};
RA Cohen D.B., Kent A.D.;
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LT985188; SPD88446.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2N9JKZ3; -.
DR KEGG; mgg:MPLG2_3416; -.
DR OrthoDB; 9806127at2; -.
DR Proteomes; UP000238164; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18550; ABC_6TM_exporter_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF658; ABC TRANSPORTER B FAMILY MEMBER 29, CHLOROPLASTIC; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000238164};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..325
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 374..612
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 624 AA; 66705 MW; C4E604FA0E9607F1 CRC64;
MSGWQVMNSM TRDSSVRDHR LAPGTRRRVL SYAAAYKGLI AVFLGLTVID SLLVVASPLL
LQRLIDDGVI PGNAGLVIQL AVLVALIALA DATLTLVERW FSSRIGEGLI YDLRTQVFGH
VLRQPIAFFT RAQTGALVTR LNSDVIGAQQ AFTSVLQNLV GNAISLVVIV VAMASLSWQL
TLGALLLVPL FIVPARIIGR RLAGLTRRQM SLNAEMGAQM SERFNVAGAL LVKLFGDPRR
EDAEYADHAR GVRDVGVTLA VNRSVFFVAL GLVASLATAM VYGFGGVMAV NGLLTVGTLL
ALAALLARLY APLTALSNVR VDVMTALVSF ERVFEVLDLK PLVEQKPDAV DIPDEPVRVE
IDQVSFRYPS ADEISLASLE GVASGDRKGS GDILHDITFD VVPGSMVALV GPSGAGKTTI
TSLVARLYDP TEGAIRVNGV DLRDATLTSL HDRVGVVTQE AHLFHDTLRA NLLYAKPEAT
TAELEAALRA AQVWHLVESL PAGLDTVVGD RGHRLSGGEK QRFAIARLLL KGPGLVVLDE
ATAHLDSESE AAVQRALDAA LADRTSIVIA HRLSTVRGAD QILVVDDGRI VERGSHVQLL
AQGGLYADLY RTQFAEQAVT AAQT
//
