ID A0A2P1A0K1_9CAUD Unreviewed; 608 AA.
AC A0A2P1A0K1;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=DNA polymerase I {ECO:0000313|EMBL:AVI03580.1};
GN Name=45 {ECO:0000313|EMBL:AVI03580.1};
GN ORFNames=SEA_BEESKNEES_45 {ECO:0000313|EMBL:AVI03580.1};
OS Mycobacterium phage BeesKnees.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Fromanvirus.
OX NCBI_TaxID=2081620 {ECO:0000313|EMBL:AVI03580.1, ECO:0000313|Proteomes:UP000241221};
RN [1] {ECO:0000313|EMBL:AVI03580.1, ECO:0000313|Proteomes:UP000241221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Delong Z., Devault B., Huffman J., Scuttaro V., Woodford M.,
RA Washington J.M., Garlena R.A., Russell D.A., Pope W.H., Jacobs-Sera D.,
RA Hendrix R.W., Hatfull G.F.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; MG872833; AVI03580.1; -; Genomic_DNA.
DR Proteomes; UP000241221; Genome.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR GO; GO:0039693; P:viral DNA genome replication; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.370; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF27; DNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00023109};
KW Viral DNA replication {ECO:0000256|ARBA:ARBA00023109}.
FT DOMAIN 15..192
FT /note="3'-5' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00474"
FT DOMAIN 372..555
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|SMART:SM00482"
SQ SEQUENCE 608 AA; 67546 MW; 6EC6D24C7AC2C70E CRC64;
MKQHRYQIKD ETVLVNVVEH EDDLDGFESF IRSNLRILGL DTETTDLGIY KPDFGIRLIQ
FGNPWESWVL PVERGGAFVG AAVTALQKVQ RFVIHNAAFD LQVIERTLGV PMEQMWPKVE
DTKIYSHLVD PRAYKEGGTG HKLEELTKFY IDPVTAEEVK ASMARLAKKH KTTKDKIWAL
VDLDDPDYEL YAGMDTILVS RLLGKVAPLV PESSHKLIPY EHKLAEVMSY VERTGFLLDV
DYSEKLSADM LRKAEHYTAV ARYAYGVDSV NSTEKLADGL ERTGVKIKGR TATGKRQVNA
ELLEALAEEG NALAKAAIEA KKWGSWEKTW VRNFIERRDA DDRVHPGINP LQARTGRMST
SNPSAQNLPS GDWMVRRCFL ADPGQLMVSV DYQAQELRVL AALADDRTMI RAFEEEADLH
QVTADAAGMD RKVGKMANFL TVYGGGAGKL ATNAGITFPE AKKVLDIFAA TYPGVTDLSK
SLQREAANLG YVVTPTGRRL PVDPDRGYAA LNYMVQSTSR DVTASAVLRL HDAGLTPMIR
LVIHDEVLAS VPEAEAEVTA KEIGRIMEQT FRGVLINTDP EVGGRSWGAA YLKKDEQPSV
DPFLRIPA
//
