ID A0A2P1JZ98_9CAUD Unreviewed; 609 AA.
AC A0A2P1JZ98;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=DNA polymerase I {ECO:0000313|EMBL:AVO25652.1};
GN Name=45 {ECO:0000313|EMBL:AVO25652.1};
GN ORFNames=SEA_MCGUIRE_45 {ECO:0000313|EMBL:AVO25652.1};
OS Mycobacterium phage McGuire.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Fromanvirus.
OX NCBI_TaxID=2094137 {ECO:0000313|EMBL:AVO25652.1, ECO:0000313|Proteomes:UP000240964};
RN [1] {ECO:0000313|EMBL:AVO25652.1, ECO:0000313|Proteomes:UP000240964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Dolan S., O'Brien K., Edgington N.P., Aull H.G., Stoner T.H., Garlena R.A.,
RA Russell D.A., Pope W.H., Jacobs-Sera D., Hatfull G.F.;
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; MG962372; AVO25652.1; -; Genomic_DNA.
DR Proteomes; UP000240964; Genome.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR GO; GO:0039693; P:viral DNA genome replication; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.370; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF27; DNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00023109};
KW Viral DNA replication {ECO:0000256|ARBA:ARBA00023109}.
FT DOMAIN 15..192
FT /note="3'-5' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00474"
FT DOMAIN 372..555
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|SMART:SM00482"
SQ SEQUENCE 609 AA; 67656 MW; 64C57CE17C99EB47 CRC64;
MKQHRYQIKD ETVLVNVVEH EDDLDGFESF IRSNLRILGL DTETTDLGIY KPDFGIRLIQ
FGNPWESWVL PVERGGAFVG AAVTALQKVQ RFVIHNAAFD LQVIERTLGV PMEQMWPKVE
DTKIYSHLVD PRAYKEGGTG HKLEELTKFY IDPVTAEEVK ASMARLAKKH KTTKDKIWAL
VDLDDPDYEL YAGMDTILVS RLLGKVAPLV PESSHKLIPY EHKLAEVMSY VERTGFLLDV
DYSEKLSADM LRKSEHYTAV ARYAYGVDSV NSTEKLADGL ERTGVKIKGR TATGKRQVNA
ELLEALAEEG NALAKAAIEA KKWGSWEKTW VRNFIERRDA NDRVHPGINP LQARTGRMST
SNPSAQNLPS GDWMVRRCFL ADPGQIIASV DYRAQELRVL AALSGDQTML RAFKEESDLH
QVTADAAGVD RKIGKMANFL VCYGGGAGKL ATNAGITFPE AKKVLEVFAT TYPGVDTLNK
RMQQEAGSAG FITTPTGRRL PVDPDRAYSA LNYLIQSSSR DVTGAAVLRL HEAGFTPNMR
LVVHDEVLLS LPEADAEAAV KEVGQIMEQR IGPVLVNTDP EVTGKSWGSG YMDEETMARH
DAELRSRGF
//
